CDK1 Rabbit Monoclonal Antibody
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产品编号
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产品名称
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产品包装
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产品价格
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XY1516
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CDK1 Rabbit
Monoclonal Antibody
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50μl
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618.00元
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来源
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用途
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交叉反应性
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分子量
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Rabbit
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WB, IP, IF,
IHC, ICC
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H, M, R
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34.0kDa
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WB, Western blot;
IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry;
ICC,
Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent
Assay; ChIP, Chromatin
Immunoprecipitation Assay.
H, Human; M,
Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr,
Horse; Mk,
Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, ZebrXYish; All, all species expected.
配套提供了Western一抗稀释液，可以用于Western检测或其它适当用途时的一抗稀释。
建议抗体使用时的稀释比例如下(实际使用时需根据抗原水平的高低作适当调整)：
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WB
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IP
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IF
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IHC
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ICC
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FC
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ELISA
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ChIP
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1:1,000-1:2,000
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1:10-1:50
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1:50-1:200
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1:50-1:200
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1:50-1:200
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-
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-
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-
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抗体详细信息如下:
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About this
Antibody
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Name
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CDK1 Rabbit
Monoclonal Antibody
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Category
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Rabbit
Monoclonal Antibody (RabMAb); Primary antibody
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Isotype
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IgG
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Purification
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XYfinity
purification
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About the
Immunogen
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Immunogen
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Recombinant
protein
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Gene ID
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983(Human);
12534(Mouse); 54237(Rat)
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SwissProt
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P06493(Human);
P11440(Mouse); P39951(Rat)
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Synonyms
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CDC2; CDC28A;
P34CDC2
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Category
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Cell Cycle
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Background
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Cdk1 is a
small protein (approximately 34 kilodaltons), and is highly conserved. Cdk1
is comprised mostly by the bare protein kinase motif, which other protein
kinases share. Cdk1, like other kinases, contains a cleft in which ATP fits.
When bound to its cyclin partners, Cdk1 phosphorylation leads to cell cycle
progression. Given its essential role in cell cycle progression, Cdk1 is
highly regulated. Most obviously, Cdk1 is regulated by its binding with its
cyclin partners. Cyclin binding alters access to the active site of Cdk1,
allowing for Cdk1 activity; furthermore, cyclins impart specificity to Cdk1
activity. At least some cyclins contain a hydrophobic patch which may
directly interact with substrates, conferring target specificity.
Furthermore, cyclins can target Cdk1 to particular subcellular locations.
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包装清单:
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产品编号
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产品名称
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包装
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XY1516
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CDK1 Rabbit
Monoclonal Antibody
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50μl
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XY050
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Western一抗稀释液
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50ml
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-
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说明书
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1份
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保存条件:
CDK1 Rabbit
Monoclonal Antibody -20℃保存，Western一抗稀释液-20℃或4℃保存，一年有效。Western一抗稀释液优先推荐4℃保存，长期不使用可以考虑-20℃保存，但冻融可能会导致出现轻微的浑浊和少量不溶物。
注意事项:
如果本抗体用于Western blot (WB)、**荧光(IF)、**细胞化学(ICC)等实验，请注意回收使用过的稀释抗体?；厥盏目固逋ǔＶ辽倏梢灾馗词褂?span>5-10