Integrin beta 3 Rabbit Monoclonal Antibody
|
产品编号
|
产品名称
|
产品包装
|
产品价格
|
|
XY1444
|
Integrin beta
3 Rabbit Monoclonal Antibody
|
50μl
|
618.00元
|
|
来源
|
用途
|
交叉反应性
|
分子量
|
|
Rabbit
|
WB, IF, IHC,
ICC
|
H, M, R
|
87.0kDa
|
WB, Western blot;
IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry;
ICC,
Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent
Assay; ChIP, Chromatin
Immunoprecipitation Assay.
H, Human; M,
Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr,
Horse; Mk,
Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, ZebrXYish; All, all species expected.
配套提供了Western一抗稀释液，可以用于Western检测或其它适当用途时的一抗稀释。
建议抗体使用时的稀释比例如下(实际使用时需根据抗原水平的高低作适当调整)：
|
WB
|
IP
|
IF
|
IHC
|
ICC
|
FC
|
ELISA
|
ChIP
|
|
1:1,000
|
-
|
1:50-1:200
|
1:50-1:200
|
1:50-1:200
|
-
|
-
|
-
|
抗体详细信息如下:
|
About this
Antibody
|
|
Name
|
Integrin beta
3 Rabbit Monoclonal Antibody
|
|
Category
|
Rabbit
Monoclonal Antibody (RabMAb); Primary antibody
|
|
Isotype
|
IgG
|
|
Purification
|
XYfinity
purification
|
|
About the
Immunogen
|
|
Immunogen
|
Recombinant
protein
|
|
Gene ID
|
3690(Human);
16416(Mouse); 29302(Rat)
|
|
SwissProt
|
P05106(Human);
O54890(Mouse)
|
|
Synonyms
|
BDPLT16;
BDPLT2; CD61; GP3A; GPIIIa; GT
|
|
Category
|
Cytoskeletal
Signaling
|
|
Background
|
Integrins are
heterodimers composed of noncovalently associated transmembrane a and b
subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20
different receptors. Most integrin receptors bind ligands that are components
of the extracellular matrix, including Fibronectin, Collagen and Vitronectin.
Certain integrins can also bind to soluble ligands such as Fibrinogen, or to
counterreceptors on adjacent cells such as the intracellular adhesion
molecules (ICAMs), leading to aggregation of cells. Ligands serve to
cross-link or cluster integrins by binding to adjacent integrin receptors;
both receptor clustering and ligand occupancy are necessary for the
activation of integrin-mediated responses. In addition to mediating cell
adhesion and cytoskeletal organization, integrins function as signaling
receptors. Signals transduced by integrins play a role in many biological
processes, including cell growth, differentiation, migration and apoptosis.
|
包装清单:
|
产品编号
|
产品名称
|
包装
|
|
XY1444
|
Integrin beta
3 Rabbit Monoclonal Antibody
|
50μl
|
|
XY050
|
Western一抗稀释液
|
50ml
|
|
-
|
说明书
|
1份
|
保存条件:
Integrin beta 3
Rabbit Monoclonal Antibody -20℃保存，Western一抗稀释液-20℃或4℃保存，一年有效。Western一抗稀释液优先推荐4℃保存，长期不使用可以考虑-20℃保存，但冻融可能会导致出现轻微的浑浊和少量不溶物。
注意事项:
如果本抗体用于Western blot (WB)、**荧光(IF)、**细胞化学(ICC)等实验，请注意回收使用过的稀释抗体?；厥盏目固逋ǔＶ辽倏梢灾馗词褂?span>5-10