Calmodulin Rabbit Monoclonal Antibody
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产品编号
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产品名称
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产品包装
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产品价格
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XY1435
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Calmodulin
Rabbit Monoclonal Antibody
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50μl
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618.00元
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来源
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用途
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交叉反应性
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分子量
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Rabbit
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WB, IP, IF,
IHC, ICC
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H, M, R
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17.0kDa
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WB, Western blot;
IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry;
ICC,
Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent
Assay; ChIP, Chromatin
Immunoprecipitation Assay.
H, Human; M,
Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr,
Horse; Mk,
Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, ZebrXYish; All, all species expected.
配套提供了Western一抗稀释液，可以用于Western检测或其它适当用途时的一抗稀释。
建议抗体使用时的稀释比例如下(实际使用时需根据抗原水平的高低作适当调整)：
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WB
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IP
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IF
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IHC
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ICC
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FC
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ELISA
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ChIP
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1:1,000
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1:10-1:50
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1:50-1:200
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1:50-1:200
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1:50-1:200
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-
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-
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-
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抗体详细信息如下:
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About this
Antibody
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Name
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Calmodulin
Rabbit Monoclonal Antibody
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Category
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Rabbit
Monoclonal Antibody (RabMAb); Primary antibody
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Isotype
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IgG
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Purification
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XYfinity
purification
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About the
Immunogen
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Immunogen
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Recombinant
protein
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Gene ID
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801/805/808(Human);
12313/12314/12315(Mouse); 24242/24244/ 50663(Rat)
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SwissProt
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P62158(Human);
P62204(Mouse); P62161(Rat)
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Synonyms
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CALML2; CAMI;
CPVT4; DD132; PHKD; caM
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Category
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Neuronal
Signaling
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Background
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The level of
intracellular calcium is tightly regulated in all eukaryotic cells. A modest
increase in this level can result in a myriad of physiological responses,
most of which are mediated by calmodulin (CaM), the universal calcium sensor.
CaM directly modulates the activity of protein kinases and phosphatases, ion
channels and nitric oxide synthetases. It is generally involved in such
diverse processes as cell proliferation, endocytosis, cellular adhesion, protein
turn over and smooth muscle contraction. CaM (calmodulin) is an acidic
protein, 148 amino acids in length, with four helix-loop-helix calcium
binding domains. In humans, 3 distinct genes have been identified (CALM1,
CALM2 and CALM3); each encoding the identical protein. CALML3
(calmodulin-like 3, or calmodulin-related protein NB-1) shares significant
sequence identity with CaM and it is suggested that it may competitively bind
CaM substrates. Interestingly, CaM has been shown to associate with the carboxy
terminus of the dystrophin gene product, implying that it may regulate its
activity.
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包装清单:
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产品编号
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产品名称
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包装
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XY1435
|
Calmodulin
Rabbit Monoclonal Antibody
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50μl
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XY050
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Western一抗稀释液
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50ml
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-
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说明书
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1份
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保存条件:
Calmodulin
Rabbit Monoclonal Antibody -20℃保存，Western一抗稀释液-20℃或4℃保存，一年有效。Western一抗稀释液优先推荐4℃保存，长期不使用可以考虑-20℃保存，但冻融可能会导致出现轻微的浑浊和少量不溶物。
注意事项:
如果本抗体用于Western blot (WB)、**荧光(IF)、**细胞化学(ICC)等实验，请注意回收使用过的稀释抗体?；厥盏目固逋ǔＶ辽倏梢灾馗词褂?span>5-10