Lamin B1 Rabbit Monoclonal Antibody
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产品编号
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产品名称
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产品包装
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产品价格
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XY1408
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Lamin B1
Rabbit Monoclonal Antibody
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50μl
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618.00元
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来源
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用途
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交叉反应性
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分子量
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Rabbit
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WB, IP, IF,
IHC, ICC
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H, M, R
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70.0kDa
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WB, Western blot;
IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry;
ICC,
Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent
Assay; ChIP, Chromatin
Immunoprecipitation Assay.
H, Human; M,
Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr,
Horse; Mk,
Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, ZebrXYish; All, all species expected.
配套提供了Western一抗稀释液，可以用于Western检测或其它适当用途时的一抗稀释。
建议抗体使用时的稀释比例如下(实际使用时需根据抗原水平的高低作适当调整)：
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WB
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IP
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IF
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IHC
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ICC
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FC
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ELISA
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ChIP
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1:1,000
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1:10-1:50
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1:50-1:200
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1:50-1:500
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1:50-1:200
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-
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-
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-
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抗体详细信息如下:
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About this
Antibody
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Name
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Lamin B1
Rabbit Monoclonal Antibody
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Category
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Rabbit
Monoclonal Antibody (RabMAb); Primary antibody
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Isotype
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IgG
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Purification
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XYfinity
purification
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About the
Immunogen
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Immunogen
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Recombinant
protein
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Gene ID
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4001(Human);
16906(Mouse); 116685(Rat)
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SwissProt
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P20700(Human);
P14733(Mouse); P70615(Rat)
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Synonyms
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ADLD; LMN;
LMN2; LMNB
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Category
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Apoptosis
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Background
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A unique
family of cysteine proteases has been described that differs in sequence,
structure and substrate specificity from any previously described protease
family. This family, termed Ced-3/ICE, functions as key components of the
apoptotic machinery and act to destroy specific target proteins which are
critical to cellular longevity. Nuclear lamins are critical to maintaining
the integrity of the nuclear envelope and cellular morphology as components
of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner
nuclear membrane, which is thought to provide a framework for the nuclear
envelope and may also interact with chromatin. B-type lamins undergo a series
of modifications, such as farnesylation and phosphorylation. Increased
phosphorylation of the lamins occurs before envelope disintegration and
probably plays a role in regulating lamin associations. Nuclear Lamin B is
fragmented as a consequence of apoptosis by an unidentified member of the ICE
family.
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包装清单:
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产品编号
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产品名称
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包装
|
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XY1408
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Lamin B1
Rabbit Monoclonal Antibody
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50μl
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XY050
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Western一抗稀释液
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50ml
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-
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说明书
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1份
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保存条件:
Lamin B1 Rabbit
Monoclonal Antibody -20℃保存，Western一抗稀释液-20℃或4℃保存，一年有效。Western一抗稀释液优先推荐4℃保存，长期不使用可以考虑-20℃保存，但冻融可能会导致出现轻微的浑浊和少量不溶物。
注意事项:
如果本抗体用于Western blot (WB)、**荧光(IF)、**细胞化学(ICC)等实验，请注意回收使用过的稀释抗体?；厥盏目固逋ǔＶ辽倏梢灾馗词褂?span>5-10