ALDH1A1 Rabbit Monoclonal Antibody
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产品编号
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产品名称
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产品包装
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产品价格
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XY1351
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ALDH1A1 Rabbit
Monoclonal Antibody
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50μl
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618.00元
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来源
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用途
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交叉反应性
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分子量
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Rabbit
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WB, IP, IHC
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H, M, R
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55.0kDa
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WB, Western blot;
IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry;
ICC,
Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent
Assay; ChIP, Chromatin
Immunoprecipitation Assay.
H, Human; M,
Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr,
Horse; Mk,
Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, ZebrXYish; All, all species expected.
配套提供了Western一抗稀释液，可以用于Western检测或其它适当用途时的一抗稀释。
建议抗体使用时的稀释比例如下(实际使用时需根据抗原水平的高低作适当调整)：
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WB
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IP
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IF
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IHC
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ICC
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FC
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ELISA
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ChIP
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1:1,000-1:2,000
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1:10-1:50
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-
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1:50-1:200
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-
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-
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-
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-
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抗体详细信息如下:
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About this
Antibody
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Name
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ALDH1A1 Rabbit
Monoclonal Antibody
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Category
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Rabbit
Monoclonal Antibody (RabMAb); Primary antibody
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Isotype
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IgG
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Purification
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XYfinity
purification
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About the
Immunogen
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Immunogen
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Recombinant
protein
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Gene ID
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216(Human);11668(Mouse);
24188(Rat)
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SwissProt
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P00352(Human);
P24549(Mouse); P51647(Rat)
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Synonyms
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ALDC; ALDH-E1;
ALDH1; ALDH11; HEL-9; HEL-S-53e; HEL12; PUMB1; RALDH1
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Category
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Apoptosis
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Background
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Aldehyde
dehydrogenases (ALDHs) mediate NADP+-dependent oxidation of aldehydes into
acids during the detoxification of alcohol-derived acetaldehyde; metabolism
of corticosteroids, biogenic amines and neurotransmitters; and lipid
peroxidation. ALDH1A1, also designated retinal dehydrogenase 1 (RalDH1 or
RALDH1), aldehyde dehydrogenase family 1 member A1, aldehyde dehydrogenase
cytosolic, ALDHII, ALDH-E1 or ALDH E1, is a retinal dehydrogenase that
participates in the biosynthesis of retinoic acid (RA). There are two major
liver isoforms of ALDH1 that can localize to cytosolic or mitochondrial
space. The ALDH1A2 (RALDH2, RALDH2-T) gene produces three different
transcripts and also catalyzes the synthesis of RA from retinaldehyde.
ALDH1A3 (ALDH6, RALDH3, ALDH1A6) is a 37 kb gene that consists of 13 exons
and produces a major transcript of approximately 3.5 kb most abundant in
salivary gland, stomach and kidney. ALDH3A1 (stomach type, ALDH3, ALDHIII)
forms a cytoplasmic homodimer that preferentially oxidizes aromatic aldehyde
substrates. ALDH genes upregulate as a part of the oxidative stress response,
and appear to be abundant in certain tumors that have an accelerated
metabolism toward chemotherapy agents.
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包装清单:
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产品编号
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产品名称
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包装
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XY1351
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ALDH1A1 Rabbit
Monoclonal Antibody
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50μl
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XY050
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Western一抗稀释液
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50ml
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-
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说明书
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1份
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保存条件:
ALDH1A1 Rabbit
Monoclonal Antibody -20℃保存，Western一抗稀释液-20℃或4℃保存，一年有效。Western一抗稀释液优先推荐4℃保存，长期不使用可以考虑-20℃保存，但冻融可能会导致出现轻微的浑浊和少量不溶物。
注意事项:
如果本抗体用于Western blot (WB)、**荧光(IF)、**细胞化学(ICC)等实验，请注意回收使用过的稀释抗体?；厥盏目固逋ǔＶ辽倏梢灾馗词褂?span>5-10