TACC3 Rabbit Monoclonal Antibody
|
产品编号
|
产品名称
|
产品包装
|
产品价格
|
|
XY1345
|
TACC3 Rabbit
Monoclonal Antibody
|
50μl
|
618.00元
|
|
来源
|
用途
|
交叉反应性
|
分子量
|
|
Rabbit
|
WB, IF, IHC,
ICC
|
H, M, R
|
140.0kDa
|
WB, Western blot;
IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry;
ICC,
Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent
Assay; ChIP, Chromatin
Immunoprecipitation Assay.
H, Human; M,
Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr,
Horse; Mk,
Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, ZebrXYish; All, all species expected.
配套提供了Western一抗稀释液，可以用于Western检测或其它适当用途时的一抗稀释。
建议抗体使用时的稀释比例如下(实际使用时需根据抗原水平的高低作适当调整)：
|
WB
|
IP
|
IF
|
IHC
|
ICC
|
FC
|
ELISA
|
ChIP
|
|
1:1,000-1:5,000
|
-
|
1:50-1:200
|
1:50-1:200
|
1:50-1:200
|
-
|
-
|
-
|
抗体详细信息如下:
|
About this
Antibody
|
|
Name
|
TACC3 Rabbit
Monoclonal Antibody
|
|
Category
|
Rabbit
Monoclonal Antibody (RabMAb); Primary antibody
|
|
Isotype
|
IgG
|
|
Purification
|
XYfinity
purification
|
|
About the
Immunogen
|
|
Immunogen
|
Recombinant
protein
|
|
Gene ID
|
10460(Human);
360962(Mouse); 360962(Rat)
|
|
SwissProt
|
Q9Y6A5(Human);
Q9JJ11(Mouse); D3Z962(Rat)
|
|
Synonyms
|
ERIC-1; ERIC1
|
|
Category
|
Cell Cycle
|
|
Background
|
TACC1
(transforming acidic coiled coil gene 1) is one of three TACC family members,
which are thought to be involved in breast tumorigenesis. TACC1 is located on
8p11 chromosomal region that is amplified in approximately 15% of all breast
tumor samples. The short arm of chromosome 8 also contains FGFR1 whose
expression is enhanced in most breast cancer tumors. TACC family members,
TACC1, TACC2, and TACC3, map very closely to the corresponding FGFR1, FGFR2,
FGFR3 genes on chromosomes 8, 10, and 4. Subsequently, since they are
phylogenetically related, it is proposed that TACC and FGFR have similar
roles in cell growth and differentiation. Also, TACC1 contains a conserved
C-terminal region as in the Drosophila homolog, D-TACC. It has been shown
that D-TACC is necessary for normal spindle function, and the mammalian TACC
proteins appears to interact with centrosomes and microtubules in a similar
manner.
|
包装清单:
|
产品编号
|
产品名称
|
包装
|
|
XY1345
|
TACC3 Rabbit
Monoclonal Antibody
|
50μl
|
|
XY050
|
Western一抗稀释液
|
50ml
|
|
-
|
说明书
|
1份
|
保存条件:
TACC3 Rabbit
Monoclonal Antibody -20℃保存，Western一抗稀释液-20℃或4℃保存，一年有效。Western一抗稀释液优先推荐4℃保存，长期不使用可以考虑-20℃保存，但冻融可能会导致出现轻微的浑浊和少量不溶物。
注意事项:
如果本抗体用于Western blot (WB)、**荧光(IF)、**细胞化学(ICC)等实验，请注意回收使用过的稀释抗体?；厥盏目固逋ǔＶ辽倏梢灾馗词褂?span>5-10