SATB1 Rabbit Monoclonal Antibody
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产品编号
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产品名称
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产品包装
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产品价格
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XY1288
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SATB1 Rabbit
Monoclonal Antibody
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50μl
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618.00元
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来源
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用途
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交叉反应性
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分子量
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Rabbit
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WB, IP, IF,
IHC, ICC, FC
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H, M, R
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100.0kDa
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WB, Western blot;
IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry;
ICC,
Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent
Assay; ChIP, Chromatin
Immunoprecipitation Assay.
H, Human; M,
Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr,
Horse; Mk,
Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, ZebrXYish; All, all species expected.
配套提供了Western一抗稀释液，可以用于Western检测或其它适当用途时的一抗稀释。
建议抗体使用时的稀释比例如下(实际使用时需根据抗原水平的高低作适当调整)：
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WB
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IP
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IF
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IHC
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ICC
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FC
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ELISA
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ChIP
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1:1,000
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1:10-1:50
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1:50-1:200
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1:50-1:200
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1:50-1:200
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1:50-1:100
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-
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-
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抗体详细信息如下:
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About this
Antibody
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Name
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SATB1 Rabbit
Monoclonal Antibody
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Category
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Rabbit
Monoclonal Antibody (RabMAb); Primary antibody
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Isotype
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IgG
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Purification
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XYfinity
purification
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About the
Immunogen
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Immunogen
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Recombinant
protein
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Gene ID
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6304(Human);
20230(Mouse); 316164(Rat)
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SwissProt
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Q01826(Human);
Q60611(Mouse); Q5U2Y2(Rat)
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Synonyms
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DNA binding
protein SATB1; SATB homeobox 1 ; Special AT-rich sequence-binding protein 1
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Category
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Epigenetics
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Background
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The
homeoproteins CCAAT displacement protein (CDP) and special AT-rich sequence
binding protein 1 (SATB1) are transcriptional repressors of many cellular
genes, and they participate in cell development and cell type
differentiation. SATB1 is expressed primarily in thymocytes, and, like CDP,
it also contains a distinct homeobox DNA-binding domain that is essential for
DNA binding. SATB1 and CDP interact through these homeodomains and
synergistically function as mediators of gene expression. SATB1 contains an
additional domain that has a higher XYfinity for DNA and specifically
facilitates the direct association between SATB1 and the nuclear matrix
attachment regions (MARs) of DNA. MARs are specific DNA sequences that bind
to the nuclear matrix and form the base of chromosomal loops that organize
the chromosomes and regulate DNA transcription and replication within the
nucleus. The association of SATB1 with the core unwinding element within the
base-unpairing region of MARs requires both the MAR and homeobox binding
domains of SATB1.
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包装清单:
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产品编号
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产品名称
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包装
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XY1288
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SATB1 Rabbit
Monoclonal Antibody
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50μl
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XY050
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Western一抗稀释液
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50ml
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-
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说明书
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1份
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保存条件:
SATB1 Rabbit
Monoclonal Antibody -20℃保存，Western一抗稀释液-20℃或4℃保存，一年有效。Western一抗稀释液优先推荐4℃保存，长期不使用可以考虑-20℃保存，但冻融可能会导致出现轻微的浑浊和少量不溶物。
注意事项:
如果本抗体用于Western blot (WB)、**荧光(IF)、**细胞化学(ICC)等实验，请注意回收使用过的稀释抗体?；厥盏目固逋ǔＶ辽倏梢灾馗词褂?span>5-10