Caspase-9 Rabbit Monoclonal Antibody
|
产品编号
|
产品名称
|
产品包装
|
产品价格
|
|
XY1264
|
Caspase-9
Rabbit Monoclonal Antibody
|
50μl
|
618.00元
|
|
来源
|
用途
|
交叉反应性
|
分子量
|
|
Rabbit
|
WB, IP, IF,
IHC, ICC
|
H, M
|
46/35 kDa
|
WB, Western blot;
IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry;
ICC,
Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent
Assay; ChIP, Chromatin
Immunoprecipitation Assay.
H, Human; M,
Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr,
Horse; Mk,
Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, ZebrXYish; All, all species expected.
配套提供了Western一抗稀释液，可以用于Western检测或其它适当用途时的一抗稀释。
建议抗体使用时的稀释比例如下(实际使用时需根据抗原水平的高低作适当调整)：
|
WB
|
IP
|
IF
|
IHC
|
ICC
|
FC
|
ELISA
|
ChIP
|
|
1:1,000-1:5,000
|
1:10-1:50
|
1:100-1:500
|
1:50-1:200
|
1:100-1:500
|
-
|
-
|
-
|
抗体详细信息如下:
|
About this
Antibody
|
|
Name
|
Caspase-9
Rabbit Monoclonal Antibody
|
|
Category
|
Rabbit
Monoclonal Antibody (RabMAb); Primary antibody
|
|
Isotype
|
IgG
|
|
Purification
|
XYfinity
purification
|
|
About the
Immunogen
|
|
Immunogen
|
Recombinant
protein
|
|
Gene ID
|
842(Human);
12371(Mouse)
|
|
SwissProt
|
P55211(Human);
Q8C3Q9(Mouse)
|
|
Synonyms
|
APXY-3; APXY3;
ICE-LAP6; MCH6; PPP1R56
|
|
Category
|
Apoptosis
|
|
Background
|
A unique
family of cysteine proteases has been described that differs in sequence,
structure and substrate specificity from any previously described protease
family. This family, Ced-3/caspase-1, is comprised of caspase-1, caspase-2,
caspase-3, caspase-4, caspase-6, caspase-7 (also designated Mch3, ICE-LAP3 or
CMH-1), caspase-9 and caspase-10. Ced-3/caspase-1 family members function as
key components of the apoptotic machinery and act to destroy specific target
proteins which are critical to cellular longevity. Poly(ADP-ribose)
polymerase plays an integral role in surveying for DNA mutations and double
strand breaks. Caspase-3, caspase-7 and caspase-9, but not caspase-1, have
been shown to cleave the nuclear protein PARP into an apoptotic fragment.
Caspase-6, but not caspase-3, has been shown to cleave the nuclear lamins,
which are critical to maintaining the integrity of the nuclear envelope and
cellular morphology. Caspase-10 has been shown to activate caspase-3 and
caspase-7 in response to apoptotic stimuli.
|
包装清单:
|
产品编号
|
产品名称
|
包装
|
|
XY1264
|
Caspase-9
Rabbit Monoclonal Antibody
|
50μl
|
|
XY050
|
Western一抗稀释液
|
50ml
|
|
-
|
说明书
|
1份
|
保存条件:
Caspase-9 Rabbit
Monoclonal Antibody -20℃保存，Western一抗稀释液-20℃或4℃保存，一年有效。Western一抗稀释液优先推荐4℃保存，长期不使用可以考虑-20℃保存，但冻融可能会导致出现轻微的浑浊和少量不溶物。
注意事项:
如果本抗体用于Western blot (WB)、**荧光(IF)、**细胞化学(ICC)等实验，请注意回收使用过的稀释抗体?；厥盏目固逋ǔＶ辽倏梢灾馗词褂?span>5-10