DUSP6 Rabbit Monoclonal Antibody
|
产品编号
|
产品名称
|
产品包装
|
产品价格
|
|
XY1090
|
DUSP6 Rabbit
Monoclonal Antibody
|
50μl
|
618.00元
|
|
来源
|
用途
|
交叉反应性
|
分子量
|
|
Rabbit
|
WB, IP, IF,
IHC, ICC, FC
|
H, M, R
|
42.0kDa
|
WB, Western blot;
IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry;
ICC,
Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent
Assay; ChIP, Chromatin
Immunoprecipitation Assay.
H, Human; M,
Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr,
Horse; Mk,
Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, ZebrXYish; All, all species expected.
配套提供了Western一抗稀释液，可以用于Western检测或其它适当用途时的一抗稀释。
建议抗体使用时的稀释比例如下(实际使用时需根据抗原水平的高低作适当调整)：
|
WB
|
IP
|
IF
|
IHC
|
ICC
|
FC
|
ELISA
|
ChIP
|
|
1:1000-1:5000
|
1:50-1:200
|
1:50-1:200
|
1:50-1:200
|
1:50-1:200
|
1:50-1:100
|
-
|
-
|
抗体详细信息如下:
|
About this
Antibody
|
|
Name
|
DUSP6 Rabbit
Monoclonal Antibody
|
|
Category
|
Rabbit
Monoclonal Antibody (RabMAb); Primary antibody
|
|
Isotype
|
IgG
|
|
Purification
|
XYfinity
purification
|
|
About the
Immunogen
|
|
Immunogen
|
Recombinant
protein
|
|
Gene ID
|
1848(Human);
67603(Mouse); 116663(Rat)
|
|
SwissProt
|
Q16828(Human);
Q9DBB1(Mouse); Q64346(Rat)
|
|
Synonyms
|
HH19; MKP3;
PYST1
|
|
Category
|
MAPK
|
|
Background
|
Mitogen-activated
protein (MAP) kinases are a large class of proteins involved in signal
transduction pathways that are activated by a range of stimuli and mediate a
number of physiological and pathological changes in the cell. Dual
specificity phosphatases (DSPs) are a subclass of the protein tyrosine
phosphatase (PTP) gene superfamily, which are selective for dephosphorylating
critical phosphothreonine and phosphotyrosine residues within MAP kinases.
DSP gene expression is induced by a host of growth factors and/or cellular
stresses, thereby negatively regulating MAP kinase superfamily members
including MAPK/ERK, SAPK/JNK and p38. The members of the dual-specificity
phosphatase protein family include MKP-1/CL100 (3CH134), VHR, PAC1, MKP-2,
hVH-3 (B23), hVH-5, MKP-3, MKP-X, and MKP-4. Human MKP-3 maps to chromosome
12q22-q23 and encodes a 381 amino acid protein that specifically inactivates
members of the ERK family and is expressed in a variety of tissues with the
highest levels in heart and pancreas.
|
包装清单:
|
产品编号
|
产品名称
|
包装
|
|
XY1090
|
DUSP6 Rabbit
Monoclonal Antibody
|
50μl
|
|
XY050
|
Western一抗稀释液
|
50ml
|
|
-
|
说明书
|
1份
|
保存条件:
DUSP6 Rabbit
Monoclonal Antibody -20℃保存，Western一抗稀释液-20℃或4℃保存，一年有效。Western一抗稀释液优先推荐4℃保存，长期不使用可以考虑-20℃保存，但冻融可能会导致出现轻微的浑浊和少量不溶物。
注意事项:
如果本抗体用于Western blot (WB)、**荧光(IF)、**细胞化学(ICC)等实验，请注意回收使用过的稀释抗体?；厥盏目固逋ǔＶ辽倏梢灾馗词褂?span>5-10