Cytokeratin 17 Rabbit Monoclonal Antibody
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产品编号
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产品名称
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产品包装
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产品价格
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XY1084
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Cytokeratin 17
Rabbit Monoclonal Antibody
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50μl
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618.00元
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来源
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用途
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交叉反应性
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分子量
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Rabbit
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WB, IP, IF,
IHC, ICC, FC
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H, M, R
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48.0kDa
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WB, Western blot;
IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry;
ICC,
Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent
Assay; ChIP, Chromatin
Immunoprecipitation Assay.
H, Human; M,
Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr,
Horse; Mk,
Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, ZebrXYish; All, all species expected.
配套提供了Western一抗稀释液，可以用于Western检测或其它适当用途时的一抗稀释。
建议抗体使用时的稀释比例如下(实际使用时需根据抗原水平的高低作适当调整)：
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WB
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IP
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IF
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IHC
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ICC
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FC
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ELISA
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ChIP
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1:500-1:1000
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1:50-1:200
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1:50-1:200
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1:50-1:200
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1:50-1:200
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1:50-1:100
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-
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-
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抗体详细信息如下:
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About this
Antibody
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Name
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Cytokeratin 17
Rabbit Monoclonal Antibody
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Category
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Rabbit
Monoclonal Antibody (RabMAb); Primary antibody
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Isotype
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IgG
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Purification
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XYfinity
purification
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About the
Immunogen
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Immunogen
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Recombinant
protein
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Gene ID
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3872(Human);
16667(Mouse); 287702(Rat)
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SwissProt
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Q04695(Human);
Q9QWL7(Mouse); Q6IFU8(Rat)
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Synonyms
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PC; K17; PC2;
39.1; CK-17; PCHC1; KRT17
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Category
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Cytoskeletal
Signaling
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Background
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Cytokeratin 17
is a member of the Cytokeratin subfamily of intermediate filament proteins
(IFPs). It is unique in that it is normally expressed in the basal cells of
complex epithelia but not in stratified or simple epithelia. Cytokeratin 17
contains 432 amino acids and is expressed in the nail bed, hair follicle,
sebaceous glands and other epidermal appendages. Cytokeratin 17 functions to
regulate cell growth and size through its interactions with the adaptor
protein 14-3-3-sigma to mediate protein synthesis. Mutations in the gene
encoding for Cytokeratin 17 lead to depressed protein translation and smaller
sized skin keratinocytes, corresponding to decreased Akt/mTOR signaling
activity. Cytokeratin 17 may be a useful marker for cervical stem cell
identification, squamous cell carcinoma of the larynx, respiratory syncytial
virus and transitional cell carcinomas of the human urinary tract.
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包装清单:
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产品编号
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产品名称
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包装
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XY1084
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Cytokeratin 17
Rabbit Monoclonal Antibody
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50μl
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XY050
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Western一抗稀释液
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50ml
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-
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说明书
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1份
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保存条件:
Cytokeratin 17
Rabbit Monoclonal Antibody -20℃保存，Western一抗稀释液-20℃或4℃保存，一年有效。Western一抗稀释液优先推荐4℃保存，长期不使用可以考虑-20℃保存，但冻融可能会导致出现轻微的浑浊和少量不溶物。
注意事项:
如果本抗体用于Western blot (WB)、**荧光(IF)、**细胞化学(ICC)等实验，请注意回收使用过的稀释抗体?；厥盏目固逋ǔＶ辽倏梢灾馗词褂?span>5-10