JNK1+JNK2+JNK3 Rabbit Monoclonal Antibody
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产品编号
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产品名称
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产品包装
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产品价格
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XY1048
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JNK1+JNK2+JNK3
Rabbit Monoclonal Antibody
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50μl
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618.00元
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来源
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用途
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交叉反应性
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分子量
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Rabbit
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WB, IP, IF,
ICC
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H, M, R,Cw,
Mk, Z
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46/54 kDa
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WB, Western blot;
IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry;
ICC,
Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent
Assay; ChIP, Chromatin
Immunoprecipitation Assay.
H, Human; M,
Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr,
Horse; Mk,
Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, ZebrXYish; All, all species expected.
配套提供了Western一抗稀释液，可以用于Western检测或其它适当用途时的一抗稀释。
建议抗体使用时的稀释比例如下(实际使用时需根据抗原水平的高低作适当调整)：
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WB
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IP
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IF
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IHC
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ICC
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FC
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ELISA
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ChIP
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1:1000-1:5000
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1:50-1:200
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1:50-1:200
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-
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1:50-1:200
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-
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-
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-
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抗体详细信息如下:
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About this
Antibody
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Name
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JNK1+JNK2+JNK3
Rabbit Monoclonal Antibody
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Category
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Rabbit
Monoclonal Antibody (RabMAb); Primary antibody
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Isotype
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IgG
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Purification
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XYfinity
purification
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About the
Immunogen
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Immunogen
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Recombinant
protein
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Gene ID
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5599/5601/5602(Human);
26414/26419/26420(Mouse); 116554/50658/25272(Rat)
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SwissProt
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P45983/P45984/P53779(Human);
Q61831/Q91Y86/Q9WTU6 (Mouse); P49185/P49186/P49187(Rat)
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Synonyms
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C Jun kinase
2; c Jun N terminal kinase 1; c Jun N terminal kinase 2; c Jun N terminal
kinase 3; c-Jun N-terminal kinase 1; JNK 46; JNK 55; JNK; MAP kinase 10; MAP
kinase 9; MAP kinase 8;Mitogen activated protein kinase 10; Mitogen activated
protein kinase 9; Mitogen activated protein kinase 8; PRKM9; PRKM8; PRKM10
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Category
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MAPK
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Background
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c-Jun
N-terminal kinases (JNKs) phosphorylate and augment transcriptional activity
of c-Jun. JNKs originate from three genes that yield 10 isoforms through
alternative mRNA splicing, including JNK1a1,JNK1b1, JNK2a1, JNK2b1, and
JNK3a1, which represent the p46 isoforms, and JNK1a2, JNK1b2, JNK2a2, JNK2b2,
and JNK3b2, which represent the p54 isoforms.JNKs coordinate cell responses
to stress and influence regulation of cell growth and transformation. The
human JNK1 (PRKM8, SAPK1, MAPK8) gene maps to chromosome 10q11.22 and shares
83% amino acid identity with JNK2. JNK1 is necessary for normal activation
and differentiation of CD4 helper T (TH) cells into TH1 and TH2 effector
cells. Capsaicin activates JNK1 and p38 in ras-transformed human breast
epithelial cells. Nitrogen oxides (NOx) upregulate JNK1 in addition to c-Fos,
c-Jun, and other signaling kinases, including MEKK1 and p38.
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包装清单:
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产品编号
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产品名称
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包装
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XY1048
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JNK1+JNK2+JNK3
Rabbit Monoclonal Antibody
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50μl
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XY050
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Western一抗稀释液
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50ml
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-
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说明书
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1份
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保存条件:
JNK1+JNK2+JNK3 Rabbit Monoclonal Antibody -20℃保存，Western一抗稀释液-20℃或4℃保存，一年有效。Western一抗稀释液优先推荐4℃保存，长期不使用可以考虑-20℃保存，但冻融可能会导致出现轻微的浑浊和少量不溶物。
注意事项:
如果本抗体用于Western blot (WB)、**荧光(IF)、**细胞化学(ICC)等实验，请注意回收使用过的稀释抗体?；厥盏目固逋ǔＶ辽倏梢灾馗词褂?span>5-10