p75 NGF Receptor Rabbit Monoclonal Antibody
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产品编号
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产品名称
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产品包装
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产品价格
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XY1033
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p75 NGF
Receptor Rabbit Monoclonal Antibody
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50μl
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618.00元
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来源
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用途
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交叉反应性
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分子量
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Rabbit
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WB, IP, IF,
IHC, ICC
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H, M, R
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75.0kDa
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WB, Western blot;
IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry;
ICC,
Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent
Assay; ChIP, Chromatin
Immunoprecipitation Assay.
H, Human; M,
Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr,
Horse; Mk,
Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, ZebrXYish; All, all species expected.
配套提供了Western一抗稀释液，可以用于Western检测或其它适当用途时的一抗稀释。
建议抗体使用时的稀释比例如下(实际使用时需根据抗原水平的高低作适当调整)：
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WB
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IP
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IF
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IHC
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ICC
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FC
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ELISA
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ChIP
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1:1000-1:5000
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1:50-1:200
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1:50-1:200
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1:50-1:200
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1:50-1:200
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-
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-
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-
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抗体详细信息如下:
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About this
Antibody
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Name
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p75 NGF
Receptor Rabbit Monoclonal Antibody
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Category
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Rabbit
Monoclonal Antibody (RabMAb); Primary antibody
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Isotype
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IgG
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Purification
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XYfinity
purification
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About the
Immunogen
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Immunogen
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Recombinant
protein
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Gene ID
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4804(Human);
24596(Mouse)
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SwissProt
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P08138(Human);
Q9Z0W1(Mouse); P07174(Rat)
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Synonyms
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CD271; p75NTR;
TNFRSF16; p75(NTR); Gp80-LNGFR; NGFR
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Category
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Cell Cycle
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Background
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The Trk
oncogene encodes a membrane-spanning protein tyrosine kinase, gp140Trk, whose
expression is restricted in vivo to neurons of the sensory spinal and cranial
ganglia of neural crest origin. Nerve growth factor (NGF) stimulates tyrosine
phosphorylation of Trk A in neural cell lines and in embryonic dorsal root
ganglia. Tyrosine phosphorylation of Trk by NGF is rapid, specific and occurs
with picomolar quantities of factor, indicating that the response is mediated
by physiological amounts of NGF, suggesting that Trk A participates in the
primary signal transduction mechanism of NGF. An additional component of the
Trk A receptor complex, NGFR p75, binds to the neurotrophic factors with low XYfinity
but is required for efficient signaling. NGFR p75 accelerates Trk A
activation and may recruit downstream effector molecules to the liganded
complex.
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包装清单:
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产品编号
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产品名称
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包装
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XY1033
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p75 NGF
Receptor Rabbit Monoclonal Antibody
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50μl
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XY050
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Western一抗稀释液
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50ml
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-
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说明书
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1份
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保存条件:
p75 NGF Receptor Rabbit Monoclonal Antibody -20℃保存，Western一抗稀释液-20℃或4℃保存，一年有效。Western一抗稀释液优先推荐4℃保存，长期不使用可以考虑-20℃保存，但冻融可能会导致出现轻微的浑浊和少量不溶物。
注意事项:
如果本抗体用于Western blot (WB)、**荧光(IF)、**细胞化学(ICC)等实验，请注意回收使用过的稀释抗体?；厥盏目固逋ǔＶ辽倏梢灾馗词褂?span>5-10