Cytokeratin 19 Rabbit Monoclonal Antibody
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产品编号
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产品名称
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产品包装
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产品价格
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XY1006
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Cytokeratin 19
Rabbit Monoclonal Antibody
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50μl
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618.00元
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来源
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用途
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交叉反应性
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分子量
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Rabbit
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WB, IP, IF,
IHC, ICC, FC
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H, M
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40.0kDa
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WB, Western blot;
IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry;
ICC,
Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent
Assay; ChIP, Chromatin
Immunoprecipitation Assay.
H, Human; M,
Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr,
Horse; Mk,
Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, ZebrXYish; All, all species expected.
配套提供了Western一抗稀释液，可以用于Western检测或其它适当用途时的一抗稀释。
建议抗体使用时的稀释比例如下(实际使用时需根据抗原水平的高低作适当调整)：
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WB
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IP
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IF
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IHC
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ICC
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FC
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ELISA
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ChIP
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1:1,000-1:2,000
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1:10-1:40
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1:10-1:40
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1:10-1:40
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1:10-1:40
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1:2-1:20
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-
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-
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抗体详细信息如下:
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About this
Antibody
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Name
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Cytokeratin 19
Rabbit Monoclonal Antibody
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Category
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Rabbit
Monoclonal Antibody (RabMAb); Primary antibody
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Isotype
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IgG
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Purification
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XYfinity
purification
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About the
Immunogen
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Immunogen
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Recombinant
protein
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Gene ID
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3880(Human);
16669(Mouse)
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SwissProt
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P08727(Human);
P19001(Mouse)
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Synonyms
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K19; CK19;
K1CS; KRT19
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Category
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Cytoskeletal
Signaling
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Background
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Cytokeratins
comprise a diverse group of intermediate filament proteins (IFPs) that are
expressed as pairs in both keratinized and non-keratinized epithelial tissue.
Cytokeratins play a critical role in differentiation and tissue
specialization and function to maintain the overall structural integrity of
epithelial cells and have been found to be useful markers of tissue
differentiation, which is directly applicable to the characterization of
malignant tumors. For example, many types of cancer cells express Cytokeratin
19 (CK19), an epithelial cytoskeletal protein within the suprabasal squamous
epithelium. Cytokeratin 19 is a specific marker of moderate to severe
dysplasia and carcinoma in situ in oral cavity squamous epithelium, and
measurement of Cytokeratin 19 may be a useful marker in diagnosing hepatoma.
Cytokeratin 19 fragment levels in serum have been documented as a marker for
lung cancer. Clinical investigations have suggested that serum CYFRA 21-1, a
fragment of Cytokeratin 19, may be among the most useful tumor markers.
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包装清单:
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产品编号
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产品名称
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包装
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XY1006
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Cytokeratin 19
Rabbit Monoclonal Antibody
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50μl
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XY050
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Western一抗稀释液
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50ml
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-
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说明书
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1份
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保存条件:
Cytokeratin 19
Rabbit Monoclonal Antibody -20℃保存，Western一抗稀释液-20℃或4℃保存，一年有效。Western一抗稀释液优先推荐4℃保存，长期不使用可以考虑-20℃保存，但冻融可能会导致出现轻微的浑浊和少量不溶物。
注意事项:
如果本抗体用于Western blot (WB)、**荧光(IF)、**细胞化学(ICC)等实验，请注意回收使用过的稀释抗体?；厥盏目固逋ǔＶ辽倏梢灾馗词褂?span>5-10