p70 S6 Kinase β Rabbit Polyclonal Antibody
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产品编号
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产品名称
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产品包装
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产品价格
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XY0258
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p70 S6 Kinase β Rabbit Polyclonal Antibody
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50μl
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416.00元
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来源
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用途
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交叉反应性
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分子量
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Rabbit
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WB, FC, IHC,
ICC, IF
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H, M, R
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70KDa
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WB, Western blot;
IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry;
ICC,
Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent
Assay; ChIP, Chromatin
Immunoprecipitation Assay.
H, Human; M,
Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr,
Horse; Mk,
Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, ZebrXYish; All, all species expected.
配套提供了Western一抗稀释液，可以用于Western检测或其它适当用途时的一抗稀释。
建议抗体使用时的稀释比例如下(实际使用时需根据抗原水平的高低作适当调整)：
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WB
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IP
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IF
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IHC
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ICC
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FC
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ELISA
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ChIP
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1:500-1:1000
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-
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1:200
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1:200
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1:200
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1:100-1:200
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-
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-
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抗体详细信息如下:
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About this
Antibody
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Name
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p70 S6 Kinase β Rabbit Polyclonal Antibody
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Category
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Polyclonal
antibody(pAb); Primary antibody
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Isotype
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IgG
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Purification
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Peptide XYfinity
purified
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About the
Immunogen
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Immunogen
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This antibody
is produced by immunizing rabbits with a synthetic peptide (KLH-coupled)
corresponding to p70 S6 Kinase beta.
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Gene ID
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6198
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SwissProt
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P23443
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Synonyms
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EC 2.7.11.1;
KS6B1; P70-S6K; RPS6KB1; Ribosomal protein S6 kinase; Ribosomal protein S6
kinase; 70kDa; polypeptide 1; S6K; kinase p70S6K; p70-S6K
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Category
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PI3K/Akt
Signaling
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Background
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p70 S6 kinase
is a mitogen activated Ser/Thr protein kinase that is required for cell
growth and G1 cell cycle progression. p70 S6 kinase phosphorylates the S6
protein of the 40S ribosomal subunit and is involved in translational control
of 5' oligopyrimidine tract mRNAs. A second isoform, p85 S6 kinase, is
derived from the same gene and is identical to p70 S6 kinase except for 23
extra residues at the amino terminus, which encode a nuclear localizing
signal. Both isoforms lie on a mitogen activated signaling pathway downstream
of phosphoinositide-3 kinase (PI-3K) and the target of rapamycin, FRAP/mTOR,
a pathway distinct from the Ras/MAP kinase cascade. Ribosomal protein S6
kinase beta-2 is an enzyme that in humans is encoded by the RPS6KB2 gene.
Phosphorylation of S6 leads to an increase in protein synthesis and cell
proliferation.
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包装清单：
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产品编号
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产品名称
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包装
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XY0258
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p70 S6 Kinase β Rabbit Polyclonal Antibody
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50μl
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AZ050
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Western一抗稀释液
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50ml
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—
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说明书
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1份
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保存条件：
p70 S6 Kinase β Rabbit Polyclonal Antibody -20℃保存，Western一抗稀释液-20℃或4℃保存，一年有效。Western一抗稀释液优先推荐4℃保存，长期不使用可以考虑-20℃保存，但冻融可能会导致出现轻微的浑浊和少量不溶物。
注意事项：
如果本抗体用于Western blot (WB)、**荧光(IF)、**细胞化学(ICC)等实验，请注意回收使用过的稀释抗体?；厥盏目固逋ǔＶ辽倏梢灾馗词褂?span>5-10