MMP2 Rabbit Polyclonal Antibody
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产品编号
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产品名称
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产品包装
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产品价格
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XY0234
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MMP2 Rabbit
Polyclonal Antibody
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50μl
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416.00元
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来源
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用途
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交叉反应性
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分子量
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Rabbit
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WB, FC, IHC,
ICC, IF
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H, M, R
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74KDa
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WB, Western blot;
IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry;
ICC,
Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent
Assay; ChIP, Chromatin
Immunoprecipitation Assay.
H, Human; M,
Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr,
Horse; Mk,
Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, ZebrXYish; All, all species expected.
配套提供了Western一抗稀释液，可以用于Western检测或其它适当用途时的一抗稀释。
建议抗体使用时的稀释比例如下(实际使用时需根据抗原水平的高低作适当调整)：
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WB
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IP
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IF
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IHC
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ICC
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FC
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ELISA
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ChIP
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1:1000
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-
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1:200
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1:200
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1:200
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1:100
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-
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-
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抗体详细信息如下:
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About this
Antibody
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Name
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MMP2 Rabbit
Polyclonal Antibody
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Category
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Polyclonal
antibody(pAb); Primary antibody
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Isotype
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IgG
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Purification
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Peptide XYfinity
purified
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About the
Immunogen
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Immunogen
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This antibody
is produced by immunizing rabbits with a synthetic peptide (KLH-coupled)
corresponding to MMP2.
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Gene ID
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4313
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SwissProt
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P08253
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Synonyms
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CLG4; MONA;
CLG4A; TBE-1; MMP-II
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Category
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Adhesion/ECM
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Background
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Proteins of
the matrix metalloproteinase (MMP) family are involved in the breakdown of
extracellular matrix in normal physiological processes, such as embryonic
development, reproduction, and tissue remodeling, as well as in disease
processes, such as arthritis and metastasis. Most MMP's are secreted as
inactive proproteins which are activated when cleaved by extracellular
proteinases. Activation of MMP-2 requires proteolytic processing. A complex
of membrane type 1 MMP (MT1-MMP/MMP14) and tissue inhibitor of
metalloproteinase 2 recruits pro-MMP 2 from the extracellular milieu to the
cell surface. Activation then requires an active molecule of MT1-MMP and auto
catalytic cleavage. Clustering of integrin chains promotes activation of
MMP-2. Mutations in the MMP2 gene are associated with Torg-Winchester
syndrome, multicentric osteolysis, arthritis syndrome, and possibly keloids.
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包装清单：
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产品编号
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产品名称
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包装
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XY0234
|
MMP2 Rabbit
Polyclonal Antibody
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50μl
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AZ050
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Western一抗稀释液
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50ml
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—
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说明书
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1份
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保存条件：
MMP2 Rabbit
Polyclonal Antibody -20℃保存，Western一抗稀释液-20℃或4℃保存，一年有效。Western一抗稀释液优先推荐4℃保存，长期不使用可以考虑-20℃保存，但冻融可能会导致出现轻微的浑浊和少量不溶物。
注意事项：
如果本抗体用于Western blot (WB)、**荧光(IF)、**细胞化学(ICC)等实验，请注意回收使用过的稀释抗体?；厥盏目固逋ǔＶ辽倏梢灾馗词褂?span>5-10