EPCAM Mouse Monoclonal Antibody
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产品编号
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产品名称
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产品包装
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产品价格
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XY0141
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EPCAM Mouse
Monoclonal Antibody
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50μl
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416.00元
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来源
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用途
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交叉反应性
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分子量
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Mouse
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WB, FC, IHC,
ICC, IF
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H, M
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35KDa
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WB, Western blot;
IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry;
ICC,
Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent
Assay; ChIP, Chromatin Immunoprecipitation Assay.
H, Human; M,
Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr,
Horse; Mk,
Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, ZebrXYish; All, all species expected.
配套提供了Western一抗稀释液，可以用于Western检测或其它适当用途时的一抗稀释。
建议抗体使用时的稀释比例如下(实际使用时需根据抗原水平的高低作适当调整)：
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WB
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IP
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IF
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IHC
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ICC
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FC
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ELISA
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ChIP
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1:1000-1:2000
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-
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1:100-1:200
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1:200-1:500
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1:100-1:200
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1:100-1:200
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-
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-
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抗体详细信息如下:
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About this
Antibody
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Name
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EPCAM Mouse
Monoclonal Antibody
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Category
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Monoclonal
antibody(mAb); Primary antibody
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Isotype
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IgM
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Purification
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ProL XYfinity
purified
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About the
Immunogen
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Immunogen
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This antibody
is produced by immunizing mice with recombinant protein corresponding to a
region of EpCAM .
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Gene ID
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4072
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SwissProt
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P16422
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Synonyms
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ESA; KSA;
M4S1; MK-1; DIAR5; EGP-2;EGP40; KS1/4; MIC18; TROP1; TACSTD1; EPCAM
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Category
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Adhesion/ECM
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Background
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Epithelial
cell adhesion molecule (EpCAM) is a transmembrane glycoprotein mediating
Ca2+-independent homotypic cell-cell adhesion in epithelia. EpCAM is also
involved in cell signaling, migration, proliferation, and differentiation.
Additionally, EpCAM has oncogenic potential via its capacity to upregulate
c-myc, e-fabp, and cyclins A & E. Since EpCAM is expressed exclusively in
epithelia and epithelial-derived neoplasms, EpCAM can be used as diagnostic
marker for various cancers. It appears to play a role in tumorigenesis and
metastasis of carcinomas, so it can also act as a potential prognostic marker
and as a potential target for immunotherapeutic strategies. Mutations in
EpCAM have also been associated with congenital tufting enteropathy which
causes intractable diarrhea in newborn children .
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包装清单：
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产品编号
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产品名称
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包装
|
|
XY0141
|
EPCAM Mouse
Monoclonal Antibody
|
50μl
|
|
AZ050
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Western一抗稀释液
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50ml
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|
—
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说明书
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1份
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保存条件：
EPCAM Mouse
Monoclonal Antibody -20℃保存，Western一抗稀释液-20℃或4℃保存，一年有效。Western一抗稀释液优先推荐4℃保存，长期不使用可以考虑-20℃保存，但冻融可能会导致出现轻微的浑浊和少量不溶物。
注意事项：
如果本抗体用于Western blot (WB)、**荧光(IF)、**细胞化学(ICC)等实验，请注意回收使用过的稀释抗体?；厥盏目固逋ǔＶ辽倏梢灾馗词褂?span>5-10