CDK6 Rabbit Polyclonal Antibody
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产品编号
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产品名称
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产品包装
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产品价格
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XY0114
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CDK6 Rabbit
Polyclonal Antibody
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50μl
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416.00元
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来源
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用途
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交叉反应性
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分子量
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Rabbit
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WB, IHC, ICC,
IF
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H, M, R
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37KDa
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WB, Western blot;
IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry;
ICC,
Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent
Assay; ChIP, Chromatin
Immunoprecipitation Assay.
H, Human; M,
Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr,
Horse; Mk,
Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, ZebrXYish; All, all species expected.
配套提供了Western一抗稀释液,可以用于Western检测或其它适当用途时的一抗稀释。
建议抗体使用时的稀释比例如下(实际使用时需根据抗原水平的高低作适当调整):
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WB
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IP
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IF
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IHC
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ICC
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FC
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ELISA
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ChIP
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1:1000
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-
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1:100
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1:100
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1:100
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-
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-
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-
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抗体详细信息如下:
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About this
Antibody
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Name
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CDK6 Rabbit
Polyclonal Antibody
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Category
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Polyclonal
antibody(pAb); Primary antibody
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Isotype
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IgG
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Purification
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Peptide XYfinity
purified
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About the
Immunogen
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Immunogen
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This antibody
is produced by immunizing rabbits with a synthetic peptide (KLH-coupled)
corresponding to CDK6.
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Gene ID
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1021
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SwissProt
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Q00534
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Synonyms
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PLSTIRE
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Category
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Cell Cycle /
Checkpoint Control
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Background
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CDK6 protein
contains a catalytic core composed of a serine/threonine domain.This protein
also contains an ATP-binding pocket, inhibitory and activating
phosphorylation sites, a PSTAIRE-like cyclin-binding domain and an activating
T-loop motif. CDK6 is involved in a positive feedback loop that activates
transcription factors through a reaction cascade. CDK6 is important for the
control of G1 to S phase transition. However, in recent years, new evidence
proved that the presence of CDK6 is not essential for proliferation in every
cell type, the cell cycle has a complex circuitry of regulation and the role
of CDK6 might be more important in certain cell types than in others, where
CDK4 or CDK2 can act as protein kinases compensating its role.
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包装清单:
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产品编号
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产品名称
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包装
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XY0114
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CDK6 Rabbit
Polyclonal Antibody
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50μl
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AZ050
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Western一抗稀释液
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50ml
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—
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说明书
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1份
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保存条件:
CDK6 Rabbit
Polyclonal Antibody -20℃保存,Western一抗稀释液-20℃或4℃保存,一年有效。Western一抗稀释液优先推荐4℃保存,长期不使用可以考虑-20℃保存,但冻融可能会导致出现轻微的浑浊和少量不溶物。
注意事项:
如果本抗体用于Western blot (WB)、**荧光(IF)、**细胞化学(ICC)等实验,请注意回收使用过的稀释抗体?;厥盏目固逋ǔV辽倏梢灾馗词褂?span>5-10