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产品名称: Recombinant Human Bcl-2
产品型号:
产品展商: XYbscience
产品文档: 无相关文档
简单介绍
Recombinant Human Bcl-2由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。Recombinant Human Bcl-2所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
Recombinant Human Bcl-2
的详细介绍
Recombinant Human Bcl-2
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产品编号
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产品名称
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产品包装
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产品价格
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XY7257-1mg
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Recombinant
Human Bcl-2
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1mg
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14367.00元
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Species
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Gene ID
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Accession
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Source
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Length
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MW
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Tag
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Human
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596
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P10415
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E. coli
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210aa
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23kDa
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－
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About this
Antibody
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Name
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Recombinant
Human Bcl-2 (Recombinant Human B-cell Lymphoma 2; rHuBcl-2)；重组人B细胞**瘤2
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Synonyms
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apoptosis
regulator Bcl-2; B-cell CLL/lymphoma 2; Bcl-2
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Purity
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>95% by
SDS-PAGE and HPLC analyses.
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Biological
Activity
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Test in
Process.
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Physical
Appearance
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Sterile
liquid.
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Formulation
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0.2μm filtered
concentrated solution in 25mM Tris-HCl, pH8.0, 100mM NaCl, 1mM DTT, 30%
Glycerol, with Tween-80.
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Endotoxin
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Less than
0.1EU/μg of rHuBcl-2 as determined by LAL
method.
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Reconstitution
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N/A
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Category
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Others
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Background
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B-cell
lymphoma 2 (Bcl-2) is the founding member of the Bcl-2 family and it is
encoded by the BCL2 gene in human. Bcl-2 forms homodimer and heterodimers
with other Bcl-2 family proteins, like BAX, BAK, BAD and Bcl-xL. Alternative
splicing of Bcl-2 results in two isoforms with similar folds despite
differences in anti-apoptotic activity. Bcl-2 suppresses apoptosis by
controlling the mitochondrial membrane permeability. It inhibits caspase
activity either by preventing the release of cytochrome c from the mitochondria
and/or by binding to the apoptosis-activating factor (APAF-1). Antibodies to
Bcl-2 can be used with immunohistochemistry to identify cells containing the
antigen. In some cases, the presence or absence of Bcl-2 staining in biopsies
may be significant for the patient's prognosis or likelihood of cancer
relapse. Mature human Bcl-2 shares 88%-90% amino acid sequence identity with
murine, rat, bovine, canine Bcl-2.
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Amino Acid
Sequence
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AHAGRTGYDN REIVMKYIHY KLSQRGYEWD
AGDVGAAPPG AAPAPGIFSS QPGHTPHPAA SRDPVARTSP LQTPAAPGAA AGPALSPVPP VVHLTLRQAG
DDFSRRYRRD FAEMSSQLHL TPFTARGRFA TVVEELFRDG VNWGRIVAFF EFGGVMCVES VNREMSPLVD
NIALWMTEYL NRHLHTWIQD NGGWDAFVEL YGPSMRPLFD
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包装清单:
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产品编号
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产品名称
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包装
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XY7257-5μg
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Recombinant
Human Bcl-2
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5μg
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XY7257-20μg
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Recombinant
Human Bcl-2
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20μg
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XY7257-100μg
|
Recombinant
Human Bcl-2
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100μg
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|
XY7257-1mg
|
Recombinant
Human Bcl-2
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1mg
|
|
-
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说明书
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1份
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保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品**于专业人员的科学研究用，不得用于临床诊断或**，不得用于食品或药品，不得存放于普通住宅内。
为了您的**和健康，请穿实验服并戴一次性手套操作。