Recombinant Human MIP-1β/CCL4
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产品名称: Recombinant Human MIP-1β/CCL4
产品型号:
产品展商: XYbscience
产品文档: 无相关文档
简单介绍
Recombinant Human MIP-1β/CCL4由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。Recombinant Human MIP-1β/CCL4所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
Recombinant Human MIP-1β/CCL4
的详细介绍
Recombinant Human MIP-1β/CCL4
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产品编号
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产品名称
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产品包装
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产品价格
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XY6587-1mg
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Recombinant
Human MIP-1β/CCL4
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1mg
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15444.00元
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Species
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Gene ID
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Accession
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Source
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Length
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MW
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Tag
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Human
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6351
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P13236
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E. coli
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69aa
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7.8kDa
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－
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About this
Antibody
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Name
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Recombinant
Human MIP-1β/CCL4 (Recombinant Human Macrophage Inflammatory
Protein-1β/CCL4; rHuMIP-1β/CCL4)；重组人巨噬细胞炎症蛋白1β/CCL4
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Synonyms
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Exodus-3;
MIP-1 beta; ACT2; ACT-2; AT744.1; C-C motif chemokine 4; chemokine (C-C
motif) ligand 4; G-26; G-26 T-lymphocyte-secreted protein; HC21; LAG1; LAG-1;
Lymphocyte activation gene 1 protein; Macrophage inflammatory protein 1-beta;
MIP1B; MIP1B1; MIP-1-beta; MIP-1-beta(1-69); PAT 744; Protein H400; SCYA2;
SCYA4; secreted protein G-26; SIS-gamma; small inducible cytokine A4
(homologous to mouse Mip-1b); Small-inducible cytokine A4; T-cell activation
protein 2
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Purity
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>96% by
SDS-PAGE and HPLC analyses.
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Biological
Activity
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Fully
biologically active when compared to standard. The biological activity
determined by a chemotaxis bioassay using human peripheral blood monocytes is
in a concentration range of 5.0-20ng/ml.
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Physical
Appearance
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Sterile
Filtered White lyophilized (freeze-dried) powder.
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Formulation
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Lyophilized
from a 0.2μm filtered concentrated solution in 20mM PB, pH7.4,
150mM NaCl.
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Endotoxin
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Less than 1EU/μg of rHuMIP-1β/CCL4 as determined by LAL
method.
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Reconstitution
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We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled water or aqueous buffer
containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions
should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in
appropriate buffered solutions.
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Category
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Chemokines
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Background
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CCL4 encoded
by the CCL4 gene, also known as Macrophage Inflammatory Protein-1β (MIP-1β) is a CC chemokine with
specificity for CCR5 receptors and it is a major HIV-suppressive factor
produced by CD8+ T cells. It is
a monokine with inflammatory and chemokinetic properties. Recombinant CCL4
induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and
simian immunodeficiency virus (SIV). Specifically, MIP-1-beta (3-69) is also
a ligand for CCR1 and CCR2 isoform B. Recombinant human CCL4 contains 69
amino acids and it shares 77% and 80%a.a. sequence identity with murine and
rat CCL4, respectively. Both human and murine MIP-1α and MIP-1β are active on human and murine
hematopoietic cells.
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Amino Acid
Sequence
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APMGSDPPTA CCFSYTARKL PRNFVVDYYE
TSSLCSQPAV VFQTKRSKQV CADPSESWVQ EYVYDLELN
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包装清单:
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产品编号
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产品名称
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包装
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XY6587-2μg
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Recombinant
Human MIP-1β/CCL4
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2μg
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XY6587-10μg
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Recombinant
Human MIP-1β/CCL4
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10μg
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XY6587-100μg
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Recombinant
Human MIP-1β/CCL4
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100μg
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XY6587-1mg
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Recombinant
Human MIP-1β/CCL4
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1mg
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-
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说明书
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1份
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保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品**于专业人员的科学研究用，不得用于临床诊断或**，不得用于食品或药品，不得存放于普通住宅内。
为了您的**和健康，请穿实验服并戴一次性手套操作。