Recombinant Human MIP-1α/CCL3
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产品名称: Recombinant Human MIP-1α/CCL3
产品型号:
产品展商: XYbscience
产品文档: 无相关文档
简单介绍
Recombinant Human MIP-1α/CCL3由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。Recombinant Human MIP-1α/CCL3所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
Recombinant Human MIP-1α/CCL3
的详细介绍
Recombinant Human MIP-1α/CCL3
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产品编号
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产品名称
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产品包装
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产品价格
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XY6578-1mg
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Recombinant
Human MIP-1α/CCL3
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1mg
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15444.00元
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Species
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Gene ID
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Accession
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Source
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Length
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MW
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Tag
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Human
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6348
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P10147
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E. coli
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70aa
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7.8kDa
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－
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About this
Antibody
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Name
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Recombinant
Human MIP-1α/CCL3 (Recombinant Human Macrophage Inflammatory
Protein-1α/CCL3; rHuMIP-1α/CCL3)；重组人巨噬细胞炎症蛋白1α/CCL3
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Synonyms
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LD78a; MIP-1
alpha; C-C motif chemokine 3; MIP1-(a); AI323804; chemokine (C-C motif)
ligand 3; G0S19-1; LD78alpha; Mip1a; MIP-1alpha; MIP1-alpha; Scya3
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Purity
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>96% by
SDS-PAGE and HPLC analyses.
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Biological
Activity
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Fully
biologically active when compared to standard. The biological activity
determined by a chemotaxis bioassay using human monocytes is in a
concentration range of 1.0-10ng/ml.
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Physical
Appearance
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Sterile
Filtered White lyophilized (freeze-dried) powder.
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Formulation
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Lyophilized
from a 0.2μm filtered concentrated solution in 20mM PB, pH7.4,
100mM NaCl.
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Endotoxin
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Less than 1EU/μg of rHuMIP-1α/CCL3 as determined by LAL
method.
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Reconstitution
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We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled water or aqueous buffer
containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions
should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in
appropriate buffered solutions.
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Category
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Chemokines
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Background
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CCL3, also
known as macrophage inflammatory protein-1α (MIP-1α), is a cytokine belonging to the CC chemokine family that is
involved in the acute inflammatory state in the recruitment and activation of
polymorphonuclear leukocytes. Studies showed CCL3 can bind to CCR1, CCR4 and
CCR5. MIP-1α can induce a dose-dependent inhibition
of different strains of HIV-1, HIV-2, and simian immunodeficiency virus
(SIV). Recombinant human MIP-1α is a 7.8kDa protein
containing 69 amino acid residues, including the four highly conserved
cysteine residues present in CC chemokines and it shares approximately 73%, 74%
and 92% amino acid sequence homology with the murine, rat and rhesus macaque
protein.
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Amino Acid
Sequence
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ASLAADTPTA CCFSYTSRQI PQNFIADYFE
TSSQCSKPGV IFLTKRSRQV CADPSEEWVQ KYVSDLELSA
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包装清单:
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产品编号
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产品名称
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包装
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XY6578-5μg
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Recombinant
Human MIP-1α/CCL3
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5μg
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XY6578-20μg
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Recombinant
Human MIP-1α/CCL3
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20μg
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XY6578-100μg
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Recombinant
Human MIP-1α/CCL3
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100μg
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XY6578-1mg
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Recombinant
Human MIP-1α/CCL3
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1mg
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-
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说明书
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1份
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保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品**于专业人员的科学研究用，不得用于临床诊断或**，不得用于食品或药品，不得存放于普通住宅内。
为了您的**和健康，请穿实验服并戴一次性手套操作。