Recombinant Human SDF-1γ/CXCL12γ
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产品名称: Recombinant Human SDF-1γ/CXCL12γ
产品型号:
产品展商: XYbscience
产品文档: 无相关文档
简单介绍
Recombinant Human SDF-1γ/CXCL12γ由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。Recombinant Human SDF-1γ/CXCL12γ所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
Recombinant Human SDF-1γ/CXCL12γ
的详细介绍
Recombinant Human SDF-1γ/CXCL12γ
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产品编号
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产品名称
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产品包装
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产品价格
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XY6546-1mg
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Recombinant
Human SDF-1γ/CXCL12γ
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1mg
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15444.00元
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Species
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Gene ID
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Accession
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Source
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Length
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MW
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Tag
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Human
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6387
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P48061
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E. coli
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99aa
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11.6kDa
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－
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About this
Antibody
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Name
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Recombinant
Human SDF-1γ/CXCL12γ (Recombinant Human
Stromal-Cell Derived Factor-1γ/CXCL12γ; rHuSDF-1γ/CXCL12γ)；重组人基质细胞衍生因子1γ/CXCL12γ
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Synonyms
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Stromal
cell-derived factor 1; SDF-1; hSDF-1; C-X-C motif chemokine 12; Intercrine
reduced in hepatomas; IRH; hIRH; Pre-B cell growth-stimulating factor; PBSF;
CXCL12
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Purity
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>96% by
SDS-PAGE and HPLC analyses.
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Biological
Activity
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Fully
biologically active when compared to standard. The biological activity
determined by a chemotaxis bioassay using PHA and rHuIL-2 activated human
peripheral blood T-lymphocytes is in a concentration range of 30-100ng/ml.
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Physical
Appearance
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Sterile
Filtered White lyophilized (freeze-dried) powder.
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Formulation
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Lyophilized
from a 0.2μm filtered concentrated solution in PBS, pH7.4.
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Endotoxin
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Less than
0.1EU/μg of rHuSDF-1γ/CXCL12γ as determined by LAL method.
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Reconstitution
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We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled water or aqueous buffer
containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions
should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in
appropriate buffered solutions.
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Category
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Chemokines
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Background
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CXCL12 also
known as SDF-1 is belonging to the CXC chemokine family. It is encoded by the
CXCL12 gene. In recently study, Human CXCL12 is expressed as six isoforms
that differ only in the C-terminal tail. And all SDF-1 isoforms undergo
proteolytic processing of the first two N-terminal amino acids. Human SDF-1γ is synthesized as a 119 amino acid (a.a.) precursor that contains
a 21a.a. signal sequence and a 98a.a. mature region and the SDF-1γ C-terminus binds heparin in secreted SDF-1γ, or targets the isoform to the nucleolus in the absence of a
signal sequence. On the cell surface, the receptor for this chemokine is
CXCR4 and syndecan4. CXCL12 is strongly chemotactic for T-lymphocytes,
monocytes, but not neutrophils. CXCL12 is a very important factor in
carcinogenesis and the neovascularisation linked to tumor progression.
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Amino Acid
Sequence
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GKPVSLSYRC PCRFFESHVA RANVKHLKIL
NTPNCALQIV ARLKNNNRQV CIDPKLKWIQ EYLEKALNKG RREEKVGKKE KIGKKKRQKK RKAAQKRKN
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包装清单:
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产品编号
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产品名称
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包装
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XY6546-2μg
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Recombinant
Human SDF-1γ/CXCL12γ
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2μg
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XY6546-10μg
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Recombinant
Human SDF-1γ/CXCL12γ
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10μg
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XY6546-100μg
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Recombinant
Human SDF-1γ/CXCL12γ
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100μg
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XY6546-1mg
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Recombinant
Human SDF-1γ/CXCL12γ
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1mg
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-
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说明书
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1份
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保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品**于专业人员的科学研究用，不得用于临床诊断或**，不得用于食品或药品，不得存放于普通住宅内。
为了您的**和健康，请穿实验服并戴一次性手套操作。