如果您对该产品感兴趣的话,可以
产品名称: Recombinant Rat IL-21
产品型号:
产品展商: XYbscience
产品文档: 无相关文档
简单介绍
Recombinant Rat IL-21由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。Recombinant Rat IL-21所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
Recombinant Rat IL-21
的详细介绍
Recombinant Rat IL-21
|
产品编号
|
产品名称
|
产品包装
|
产品价格
|
|
XY6308-1mg
|
Recombinant
Rat IL-21
|
1mg
|
27053.00元
|
|
Species
|
Gene ID
|
Accession
|
Source
|
Length
|
MW
|
Tag
|
|
Rat
|
365769
|
A3QPB9
|
E. coli
|
129aa
|
15.2kDa
|
－
|
|
About this
Antibody
|
|
Name
|
Recombinant
Rat IL-21 (Recombinant Rat Interleukin-21; rRtIL-21)；重组大鼠白细胞介素21
|
|
Synonyms
|
IL-21Za11interleukin-21;
interleukin 21; interleukin-21 isoform
|
|
Purity
|
>96% by
SDS-PAGE and HPLC analyses.
|
|
Biological
Activity
|
Fully
biologically active when compared to standard. The ED50 as determined by a
cell proliferation assay using human N1186 cells is less than 50ng/ml,
corresponding to a specific activity of >2.0×104IU/mg.
|
|
Physical
Appearance
|
Sterile
Filtered White lyophilized (freeze-dried) powder.
|
|
Formulation
|
Lyophilized
from a 0.2μm filtered concentrated solution in PBS, pH7.4.
|
|
Endotoxin
|
Less than 1EU/μg of rRtIL-21 as determined by LAL method.
|
|
Reconstitution
|
We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled water or aqueous buffer
containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions
should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in
appropriate buffered solutions.
|
|
Category
|
Cytokine
|
|
Background
|
Rat IL-21 is
produced by CD4+ T cells in
response to antigenic stimulation and can regulating immune system cells, for
instance cytotoxic T cells and natural killer cells. The biological effects
of IL-21 include induction of differentiation of T-cells-stimulated B-cells
into plasma cells and memory B-cells, stimulation with IL-4 of IgG
production, and induction of apoptotic effects in na?ve B-cells and
stimulated B-cells in the absence of T-cell signaling. Additionally, it
promotes the anti-tumor activity of CD8+ T-cells and NK
cells. IL-21 elicits its effect through binding to IL-21R, which also
contains the gamma chain found in other cytokine receptors such as IL-2,
IL-4, IL-7, IL-9 and IL-15. IL-21 shows having much relation with clinical
illnesses, including cancer immunotherapy, viral infections and allergies.
Mature rat IL-21 shares 88%a.a. sequence identity with mouse IL-21.
|
|
Amino Acid
Sequence
|
HKSSPQRPDH LLIRLRHLMD IVEQLKIYEN
DLDPELLTAP QDVKGQCEHE AFACFQKAKL KPSNTGNNKT FINDLLAQLR RRLPAKRTGN KQRHMAKCPS
CDLYEKKTPK EFLERLKWLL QKMIHQHLS
|
包装清单:
|
产品编号
|
产品名称
|
包装
|
|
XY6308-2μg
|
Recombinant
Rat IL-21
|
2μg
|
|
XY6308-10μg
|
Recombinant
Rat IL-21
|
10μg
|
|
XY6308-100μg
|
Recombinant
Rat IL-21
|
100μg
|
|
XY6308-1mg
|
Recombinant
Rat IL-21
|
1mg
|
|
-
|
说明书
|
1份
|
保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品**于专业人员的科学研究用，不得用于临床诊断或**，不得用于食品或药品，不得存放于普通住宅内。
为了您的**和健康，请穿实验服并戴一次性手套操作。