Recombinant Human IFN-λ1/IL-29
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产品名称: Recombinant Human IFN-λ1/IL-29
产品型号:
产品展商: XYbscience
产品文档: 无相关文档
简单介绍
Recombinant Human IFN-λ1/IL-29由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。Recombinant Human IFN-λ1/IL-29所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
Recombinant Human IFN-λ1/IL-29
的详细介绍
Recombinant Human IFN-λ1/IL-29
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产品编号
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产品名称
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产品包装
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产品价格
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XY669-1mg
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Recombinant
Human IFN-λ1/IL-29
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1mg
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15444.00元
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Species
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Gene ID
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Accession
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Source
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Length
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MW
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Tag
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Human
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282618
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Q8IU54
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E. coli
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181aa
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19.8kDa
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－
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About this
Antibody
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Name
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Recombinant
Human IFN-λ1/IL-29 (Recombinant Human Interferonλ1/Interleukin-29; rHuIFN-λ1/IL-29)；重组人干扰素1/白细胞介素29
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Synonyms
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IFN-lambda 1;
cytokine Zcyto21; IFNL1; IFN-lambda-1; IL-29; interferon lambda-1;
interferon, lambda 1; interleukin 29 (interferon, lambda 1); interleukin-29;
ZCYTO21
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Purity
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>97% by
SDS-PAGE and HPLC analyses.
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Biological
Activity
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Fully
biologically active when compared to standard. The ED50 as determined by an
anti-viral assay using human HepG2 cells infected with encephalomyocarditis
is less than 5ng/ml, corresponding to a specific activity of >2.0×105IU/mg.
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Physical
Appearance
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Sterile
Filtered White lyophilized (freeze-dried) powder.
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Formulation
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Lyophilized
from a 0.2μM filtered concentrated solution in PBS, pH7.4.
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Endotoxin
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Less than 1EU/μg of rHuIFN-λ1/IL-29 as determined by LAL
method.
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Reconstitution
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We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled water or aqueous buffer
containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions
should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in
appropriate buffered solutions.
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Category
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Cytokine
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Background
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IL-28A,
IL-28B, and IL-29, also named interferon-λ2 (IFN-λ2), IFN-λ3, and IFN-λ1, respectively, are newly identified class II cytokine receptor
ligands that are distantly related to members of the IL-10 family (11-13%a.a.
sequence identity) and the type I IFN family (15-19%a.a. sequence identity).
The expression of IL-28A, B, and IL-29 is induced by virus infection or
doublestranded RNA. All three cytokines exert bioactivities that overlap
those of type I IFNs, including antiviral activity and upregulation of MHC
class I antigen expression. The three proteins signal through the same
heterodimeric receptor complex that is composed of the IL-10 receptor β (IL-10 Rβ) and a novel IL-28 receptor α (IL-28 Rα, also known as IFN-λR1). Ligand binding to the receptor complex induces Jak kinase
activation and STAT1 and STAT2 tyrosine phosphorylation.
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Amino Acid
Sequence
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GPVPTSKPTT TGKGCHIGRF KSLSPQELAS
FKKARDALEE SLKLKNWSCS SPVFPGNWDL RLLQVRERPV ALEAELALTL KVLEAAAGPA LEDVLDQPLH
TLHHILSQLQ ACIQPQPTAG PRPRGRLHHW LHRLQEAPKK ESAGCLEASV TFNLFRLLTR DLKYVADGNL
CLRTSTHPES T
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包装清单:
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产品编号
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产品名称
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包装
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XY669-5μg
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Recombinant
Human IFN-λ1/IL-29
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5μg
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XY669-20μg
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Recombinant
Human IFN-λ1/IL-29
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20μg
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XY669-100μg
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Recombinant
Human IFN-λ1/IL-29
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100μg
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XY669-1mg
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Recombinant
Human IFN-λ1/IL-29
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1mg
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-
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说明书
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1份
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保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品**于专业人员的科学研究用，不得用于临床诊断或**，不得用于食品或药品，不得存放于普通住宅内。
为了您的**和健康，请穿实验服并戴一次性手套操作。