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产品名称: Recombinant Human IFN-γ
产品型号:
产品展商: XYbscience
产品文档: 无相关文档
简单介绍
Recombinant Human IFN-γ由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。Recombinant Human IFN-γ所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
Recombinant Human IFN-γ
的详细介绍
Recombinant Human IFN-γ
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产品编号
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产品名称
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产品包装
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产品价格
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XY664-1mg
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Recombinant
Human IFN-γ
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1mg
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5665.00元
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Species
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Gene ID
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Accession
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Source
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Length
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MW
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Tag
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Human
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3458
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P01579
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E. coli
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144aa
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16.9kDa
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－
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About this
Protein
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Name
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Recombinant
Human IFN-γ (Recombinant Human Interferon-γ; rHuIFN-γ)；重组人干扰素γ
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Synonyms
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IFNG; IFG;
IFI; IFN-gamma; Immune interferon; interferon gamma; interferon, gamma
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Purity
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>98% by
SDS-PAGE and HPLC analyses.
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Biological
Activity
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Fully
biologically active when compared to standard. The ED50 as determined by a
cytotoxicity assay using HT-29 cells is less than 0.05ng/ml, corresponding to
a specific activity of >2.0×107IU/mg.
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Physical
Appearance
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Sterile
Filtered White lyophilized (freeze-dried) powder.
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Formulation
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Lyophilized
from a 0.2μm filtered concentrated solution in PBS, pH7.4.
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Endotoxin
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Less than 1EU/μg of rHuIFN-γ as determined by LAL method.
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Reconstitution
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We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled water or aqueous buffer
containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions
should be apportioned into workng aliquots and stored at ≤-20℃. Further dilutions should be made in
appropriate buffered solutions.
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Category
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Cytokine
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Background
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Interferon-gamma
(IFN-γ), also known as Type II interferon or immune
interferon, is a cytokine produced primarily by Tlymphocytes and natural
killer cells. The protein shares no significant homology with IFN-β or the various IFN-α family proteins.
Mature IFN-γ exists as noncovalently-linked
homodimers. Human IFN-γ is highly species specific
and is biologically active only in human and primate cells. IFN-γ was originally characterized based on its antiviral activities.
The protein also exerts antiproliferative, immunoregulatory and
proinflammatory activities and is thus important in host defense mechanisms.
IFN-γ induces the production of cytokines,
upregulates the expression of class I and II MHC antigens, Fc receptor and
leukocyte adhesion molecules. It modulates macrophage effector functions,
influences isotype switching and potentiates the secretion of immunoglobulins
by B cells. IFN-γ also augments TH1 cell expansion
and may be required for TH1 cell differentiation.
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Amino Acid
Sequence
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MQDPYVKEAE NLKKYFNAGH SDVADNGTLF
LGILKNWKEE SDRKMQSQI VSFYFKLFKN FKDDQSIQKS VETIKEDMNV KFFNSNKKKR DDFEKLTNYS
VTDLNVQRKA IHELIQVMAE LSPAAKTGKR KRSQMLFRGR RASQ
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包装清单:
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产品编号
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产品名称
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包装
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XY664-20μg
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Recombinant
Human IFN-γ
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20μg
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XY664-100μg
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Recombinant
Human IFN-γ
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100μg
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XY664-1mg
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Recombinant
Human IFN-γ
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1mg
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-
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说明书
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1份
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保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品**于专业人员的科学研究用，不得用于临床诊断或**，不得用于食品或药品，不得存放于普通住宅内。
为了您的**和健康，请穿实验服并戴一次性手套操作。