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产品名称: Recombinant Human CYR61
产品型号:
产品展商: XYbscience
产品文档: 无相关文档
简单介绍
Recombinant Human CYR61由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。Recombinant Human CYR61所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
Recombinant Human CYR61
的详细介绍
Recombinant Human CYR61
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产品编号
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产品名称
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产品包装
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产品价格
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XY592-1mg
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Recombinant
Human CYR61
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1mg
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20076.00元
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Species
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Gene ID
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Accession
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Source
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Length
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MW
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Tag
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Human
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3491
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O00622
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E. coli
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357aa
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39.4kDa
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－
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About this
Antibody
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Name
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Recombinant
Human CYR61 (Recombinant Human Cysteine-rich Angiogenic Inducer 61; rHuCYR61)；重组人富半胱氨酸蛋白61
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Synonyms
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CCN1; GIG1;
IGFBP-10; CCN family member 1; CCN1IGF-binding protein 10; Cysteine-rich
angiogenic inducer 61; cysteine-rich, angiogenic inducer, 61;
GIG1cysteine-rich heparin-binding protein 61; IBP-10; IGFBP-10;
IGFBP10cysteine-rich, anigogenic inducer, 61; Insulin-like growth
factor-binding protein 10; protein CYR61; Protein GIG1
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Purity
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>95% by
SDS-PAGE and HPLC analyses.
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Biological
Activity
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Fully
biologically active when compared to standard. The ED50 as determined by a
cell proliferation assay using murine Balb/3T3 cells is less than 3.0μg/ml, corresponding to a specific activity of >330IU/mg.
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Physical
Appearance
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Sterile
Filtered White lyophilized (freeze-dried) powder.
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Formulation
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Lyophilized
from a 0.2μm filtered concentrated solution in citrate buffer
solution, 300mM NaCl, pH3.0.
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Endotoxin
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Less than 1EU/μg of rHuCYR61 as determined by LAL method.
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Reconstitution
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We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled water or aqueous buffer
containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should
be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in
appropriate buffered solutions.
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Category
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Cytokine
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Background
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Cysteine-rich
angiogenic inducer 61 (Cyr61) encoded by the Cyr61 gene is a dynamically
expressed, multifunctional matricellular protein and it is also a secreted,
extracellular matrix (ECM)-associated signaling protein of the CCN family.
Cyr61 plays essential roles in cardiovascular development during
embryogenesis and regulates inflammation, wound healing and fibrogenesis in
the *****. Aberrant CCN1 expression is associated with myriad pathologies,
including various cancers and diseases associated with chronic inflammation.
Mature human Cyr61 shares 93% amino acid sequence identity with mouse and rat
Cyr61. Cyr61 consists of four domains. There are an IGFBP domain, a VWF type
C domain, a TSP type I domain, and a cysteine knot domain.
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Amino Acid
Sequence
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TCPAACHCPL EAPKCAPGVG LVRDGCGCCK
VCAKQLNEDC SKTQPCDHTK GLECNFGASS TALKGICRAQ SEGRPCEYNS RIYQNGESFQ PNCKHQCTCI
DGAVGCIPLC PQELSLPNLG CPNPRLVKVT GQCCEEWVCD EDSIKDPMED QDGLLGKELG FDASEVELTR
NNELIAVGKG SSLKRLPVFG MEPRILYNPL QGQKCIVQTT SWSQCSKTCG TGISTRVTND NPECRLVKET
RICEVRPCGQ PVYSSLKKGK KCSKTKKSPE PVRFTYAGCL SVKKYRPKYC GSCVDGRCCT PQLTRTVKMR
FRCEDGETFS KNVMMIQSCK CNYNCPHANE AAFPFYRLFN DIHKFRD
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包装清单:
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产品编号
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产品名称
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包装
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XY592-5μg
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Recombinant
Human CYR61
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5μg
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XY592-20μg
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Recombinant
Human CYR61
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20μg
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XY592-100μg
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Recombinant
Human CYR61
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100μg
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XY592-1mg
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Recombinant
Human CYR61
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1mg
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-
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说明书
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1份
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保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品**于专业人员的科学研究用，不得用于临床诊断或**，不得用于食品或药品，不得存放于普通住宅内。
为了您的**和健康，请穿实验服并戴一次性手套操作。