Recombinant Human sTNF RI/TNFRSF1A
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产品名称: Recombinant Human sTNF RI/TNFRSF1A
产品型号:
产品展商: XYbscience
产品文档: 无相关文档
简单介绍
Recombinant Human sTNF RI/TNFRSF1A由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细胞因子或重组蛋白不会粘附于管壁。Recombinant Human sTNF RI/TNFRSF1A所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
Recombinant Human sTNF RI/TNFRSF1A
的详细介绍
Recombinant Human sTNF RI/TNFRSF1A
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产品编号
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产品名称
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产品包装
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产品价格
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XY439-1mg
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Recombinant
Human sTNF RI/TNFRSF1A
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1mg
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15444.00元
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Species
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Gene ID
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Accession
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Source
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Length
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MW
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Tag
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Human
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7132
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P19438
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E. coli
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190aa
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21.2kDa
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-
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About this
Antibody
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Name
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Recombinant
Human sTNF RI/TNFRSF1A (Recombinant Human soluble Tumor Necrosis Factor
Receptor Type I/TNFRSF1A; rHusTNF RI/TNFRSF1A);重组人可溶性肿瘤坏死因子受体I型/TNFRSF1A
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Synonyms
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CD120a;
TNFRSF1A; CD120a; CD120a antigen; FPF; XY5; XY5-R; p60; TNFARMGC19588; TNF-R;
TNF-R1; TNFR1TBP1; TNFR55; TNF-R55; TNFR60; TNF-RI; TNF-R-I; TNFR-I; tumor
necrosis factor binding protein 1; Tumor necrosis factor receptor 1; tumor
necrosis factor receptor 1A isoform beta; tumor necrosis factor receptor
superfamily member 1A; tumor necrosis factor receptor superfamily, member 1A;
tumor necrosis factor receptor type 1; Tumor necrosis factor receptor type I;
tumor necrosis factor-alpha receptor
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Purity
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>97% by
SDS-PAGE and HPLC analyses.
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Biological
Activity
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Fully
biologically active when compared to standard. The ED50 as determined by its
ability to inhibit the TNF-alpha mediated cytotoxicity in the L-929 cells is
less than 0.05μg/ml, corresponding to a specific activity of >2×104IU/mg in the presence of 0.25ng/ml of rHuTNF-alpha.
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Physical
Appearance
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Sterile
Filtered White lyophilized (freeze-dried) powder.
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Formulation
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Lyophilized
from a 0.2μm filtered solution in PBS, pH7.4.
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Endotoxin
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Less than
0.1EU/μg of rHusTNF RI/TNFRSF1A as determined by LAL method.
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Reconstitution
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We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing
0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be
apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in
appropriate buffered solutions.
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Category
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Cytokine
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Background
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TNF RI, also
named as TNFR-I, TNF R1, TNFRSF1A, XY5 and p60, belongs to the tumor necrosis
factor receptor superfamily, and it is encoded by the TNFRSF1A gene in human.
TNF RI is a universally expressed protein and is thought to form homotrimers
after ligand binding. TNF RI is one of the major receptors for the TNF-α. This receptor can activate the transcription factor NF-κB, mediate apoptosis, and function as a regulator of inflammation.
Mature human soluble TNF RI shares 68%~73% amino acid sequence identity with
murine, rat, bovine and porcine soluble TNF RI.
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Amino Acid
Sequence
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IYPSGVIGLV PHLGDREKRD SVCPQGKYIH
PQNNSICCTK CHKGTYLYND CPGPGQDTDC RECESGSFTA SENHLRHCLS CSKCRKEMGQ VEISSCTVDR
DTVCGCRKNQ YRHYWSENLF QCFNCSLCLN GTVHLSCQEK QNTVCTCHAG FFLRENECVS CSNCKKSLEC
TKLCLPQIEN VKGTEDSGTT
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包装清单:
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产品编号
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产品名称
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包装
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XY439-5μg
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Recombinant
Human sTNF RI/TNFRSF1A
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5μg
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XY439-20μg
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Recombinant
Human sTNF RI/TNFRSF1A
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20μg
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XY439-100μg
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Recombinant
Human sTNF RI/TNFRSF1A
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100μg
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XY439-1mg
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Recombinant
Human sTNF RI/TNFRSF1A
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1mg
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-
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说明书
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1份
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保存条件:
-20℃或更低温度保存,至少一年有效。由于蛋白的每次冻融均会引起部分失活,所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液),须分装后-20℃或更低温度冻存,以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品**于专业人员的科学研究用,不得用于临床诊断或**,不得用于食品或药品,不得存放于普通住宅内。
为了您的**和健康,请穿实验服并戴一次性手套操作。