Recombinant Human TL-1A/TNFSF15
如果您对该产品感兴趣的话,可以
产品名称: Recombinant Human TL-1A/TNFSF15
产品型号:
产品展商: XYbscience
产品文档: 无相关文档
简单介绍
Recombinant Human TL-1A/TNFSF15由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。Recombinant Human TL-1A/TNFSF15所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
Recombinant Human TL-1A/TNFSF15
的详细介绍
Recombinant Human TL-1A/TNFSF15
|
产品编号
|
产品名称
|
产品包装
|
产品价格
|
|
XY430-1mg
|
Recombinant
Human TL-1A/TNFSF15
|
1mg
|
15444.00元
|
|
Species
|
Gene ID
|
Accession
|
Source
|
Length
|
MW
|
Tag
|
|
Human
|
9966
|
O95150
|
E. coli
|
180aa
|
20.5kDa
|
－
|
|
About this
Antibody
|
|
Name
|
Recombinant
Human TL-1A/TNFSF15 (Recombinant Human TNF Ligand-related Molecule 1/TNFSF15;
rHuTL-1A/TNFSF15)；重组人肿瘤坏死因子配体相关分子1/TNFSF15
|
|
Synonyms
|
TNFSF15; VEGI;
MGC129934; MGC129935; TL1A; TL1Vascular endothelial cell growth inhibitor;
TNF superfamily ligand TL1A; tumor necrosis factor (ligand) superfamily,
member 15; tumor necrosis factor ligand superfamily member 15; vascular
endothelial growth inhibitor-192A; VEGI192A; VEGITNF ligand-related molecule
1
|
|
Purity
|
>97% by
SDS-PAGE and HPLC analyses.
|
|
Biological
Activity
|
Fully
biologically active when compared to standard. The ED50 as determined by its
ability to induce apoptosis using human TF-1 cells is less than 20ng/ml,
corresponding to a specific activity of >5.0×104IU/mg.
|
|
Physical
Appearance
|
Sterile
Filtered White lyophilized (freeze-dried) powder.
|
|
Formulation
|
Lyophilized
from a 0.2μm filtered concentrated solution in PBS, pH7.4, with
0.02% Tween-20.
|
|
Endotoxin
|
Less than
0.1EU/μg of rHuTL-1A/TNFSF15 as determined by LAL method.
|
|
Reconstitution
|
We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled water or aqueous buffer
containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions
should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in
appropriate buffered solutions.
|
|
Category
|
Cytokine
|
|
Background
|
TL-1A is a
type II transmembrane protein belonging to the TNF superfamily and has been
designated TNF superfamily member 15 (TNFSF15). TL-1A is predominantly
expressed in endothelial cells and its expression is inducible by TNF-α and IL-1α. TL-1A binds with high affinity
to death receptor 3 (DR3), known as TNFRSF25. Depending on the cell context,
ligation of DR3 by TL-1A can trigger one of two signaling pathways,
activation of the transcription factor NF-kB, or activation of caspases and
apoptosis. Recombinant human TL-1A is a 20.5kDa polypeptide of 180 amino acid
residues.
|
|
Amino Acid
Sequence
|
LKGQEFAPSH QQVYAPLRAD GDKPRAHLTV
VRQTPTQHFK NQFPALHWEH ELGLAFTKNR MNYTNKFLLI PESGDYFIYS QVTFRGMTSE CSEIRQAGRP
NKPDSITVVI TKVTDSYPEP TQLLMGTKSV CEVGSNWFQP IYLGAMFSLQ EGDKLMVNVS DISLVDYTKE
DKTFFGAFLL
|
包装清单:
|
产品编号
|
产品名称
|
包装
|
|
XY430-5μg
|
Recombinant
Human TL-1A/TNFSF15
|
5μg
|
|
XY430-20μg
|
Recombinant
Human TL-1A/TNFSF15
|
20μg
|
|
XY430-100μg
|
Recombinant
Human TL-1A/TNFSF15
|
100μg
|
|
XY430-1mg
|
Recombinant
Human TL-1A/TNFSF15
|
1mg
|
|
-
|
说明书
|
1份
|
保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品**于专业人员的科学研究用，不得用于临床诊断或**，不得用于食品或药品，不得存放于普通住宅内。
为了您的**和健康，请穿实验服并戴一次性手套操作。