Recombinant Human sFasR/TNFRSF6
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产品名称: Recombinant Human sFasR/TNFRSF6
产品型号:
产品展商: XYbscience
产品文档: 无相关文档
简单介绍
Recombinant Human sFasR/TNFRSF6由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。Recombinant Human sFasR/TNFRSF6所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
Recombinant Human sFasR/TNFRSF6
的详细介绍
Recombinant Human sFasR/TNFRSF6
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产品编号
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产品名称
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产品包装
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产品价格
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XY412-1mg
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Recombinant
Human sFasR/TNFRSF6
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1mg
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20076.00元
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Species
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Gene ID
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Accession
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Source
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Length
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MW
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Tag
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Human
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355
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P25445
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E. coli
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157aa
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17.6kDa
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－
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About this
Antibody
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Name
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Recombinant
Human sFasR/TNFRSF6 (Recombinant Human soluble Fas Receptor/TNFRSF6;
rHusFasR/TNFRSF6)；重组人可溶性Fas受体/TNFRSF6
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Synonyms
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Apo-1; APT1;
CD95; TNFRSF6; Apo-1 antigen; apoptosis antigen 1; Apoptosis-mediating
surface antigen FAS; APT1FASTM; CD95 antigen; CD95ALPS1A; Fas (TNF receptor
superfamily, member 6); Fas AMA; Fas antigen; FAS1; FASLG receptor;
TNFRSF6member 6; tumor necrosis factor receptor superfamily member 6
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Purity
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>95% by
SDS-PAGE and HPLC analyses.
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Biological
Activity
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Fully
biologically active when compared to standard. The ED50 as determined by its
ability to inhibit the cytotoxicity of Jurkat cells is between 10-15μg/ml in the presence of 2ng/ml of rHuFas Ligand.
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Physical
Appearance
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Sterile
Filtered White lyophilized (freeze-dried) powder.
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Formulation
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Lyophilized
from a 0.2μm filtered concentrated solution in PBS, pH7.4.
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Endotoxin
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Less than 1EU/μg of rHusFasR/TNFRSF6 as determined by LAL method.
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Reconstitution
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We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled water or aqueous buffer
containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions
should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in
appropriate buffered solutions.
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Category
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Cytokine
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Background
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Fas and Fas
Ligand (FasL) belong to the TNF superfamily and are type I and type II
transmembrane proteins, respectively. Binding of FasL to Fas triggers
apoptosis in Fas-bearing cells. The mechanism of apoptosis involves
recruitment of pro-caspase 8 through an adaptor molecule called FADD followed
by processing of the pro-enzyme to active forms. These active caspases then
cleave various cellular substrates leading to the eventual cell death. sFasR
is capable of inhibiting FasL-induced apoptosis by acting as a decoy receptor
that serves as a sink for FasL.
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Amino Acid
Sequence
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RLSSKSVNAQ VTDINSKGLE LRKTVTTVET
QNLEGLHHDG QFCHKPCPPG ERKARDCTVN GDEPDCVPCQ EGKEYTDKAH FSSKCRRCRL CDEGHGLEVE
INCTRTQNTK CRCKPNFFCN STVCEHCDPC TKCEHGIIKE CTLTSNTKCK EEGSRSN
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包装清单:
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产品编号
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产品名称
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包装
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XY412-5μg
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Recombinant
Human sFasR/TNFRSF6
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5μg
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XY412-20μg
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Recombinant
Human sFasR/TNFRSF6
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20μg
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XY412-100μg
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Recombinant
Human sFasR/TNFRSF6
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100μg
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XY412-1mg
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Recombinant
Human sFasR/TNFRSF6
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1mg
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-
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说明书
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1份
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保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品**于专业人员的科学研究用，不得用于临床诊断或**，不得用于食品或药品，不得存放于普通住宅内。
为了您的**和健康，请穿实验服并戴一次性手套操作。