Recombinant Human 4-1BBL/TNFSF9
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产品名称: Recombinant Human 4-1BBL/TNFSF9
产品型号:
产品展商: XYbscience
产品文档: 无相关文档
简单介绍
Recombinant Human 4-1BBL/TNFSF9由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。Recombinant Human 4-1BBL/TNFSF9所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
Recombinant Human 4-1BBL/TNFSF9
的详细介绍
Recombinant Human 4-1BBL/TNFSF9
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产品编号
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产品名称
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产品包装
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产品价格
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XY394-1mg
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Recombinant
Human 4-1BBL/TNFSF9
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1mg
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15444.00元
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Species
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Gene ID
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Accession
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Source
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Length
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MW
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Tag
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Human
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8744
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P41273
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E. coli
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184aa
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19.4kDa
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－
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About this
Antibody
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Name
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Recombinant
Human 4-1BBL/TNFSF9 (Recombinant Human 4-1BB Ligand; rHu4-1BBL)；重组人4-1BB配体/TNFSF9
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Synonyms
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CD137L;
TNFSF9; 4-1BB ligand; 4-1BBL; 4-1BB-L; CD137L; homolog of mouse 4-1BB-L;
receptor 4-1BB ligand; tumor necrosis factor (ligand) superfamily, member 9;
tumor necrosis factor ligand superfamily member 9
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Purity
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>95% by
SDS-PAGE and HPLC analyses.
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Biological
Activity
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Fully
biologically active when compared to standard. The ED50 as determined by
stimulation of IL-8 production using human PBMC is less than 10ng/ml,
corresponding to a specific activity of >1.0×105IU/mg.
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Physical
Appearance
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Sterile
Filtered White lyophilized (freeze-dried) powder.
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Formulation
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Lyophilized
from a 0.2μm filtered concentrated solution in PBS, pH7.4.
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Endotoxin
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Less than 1EU/μg of rHu4-1BBL as determined by LAL method.
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Reconstitution
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We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled water or aqueous buffer
containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions
should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in
appropriate buffered solutions.
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Category
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Cytokine
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Background
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4-1BBL is a
member of the tumor necrosis factor (TNF) receptor family. This receptor
contributes to the clonal expansion, survival, and development of T cells. In
addition, 4-1BBL expression is found on dendritic cells, follicular dendritic
cells, natural killer cells, granulocytes and cells of blood vessel walls at
sites of inflammation. CD137 has been shown to interact with TRAF2. The human
4-1BBL gene codes for a 254 amino acid type II transmembrane containing a 28
amino acid cytoplasmic domain, a 21 amino acid transmembrane domain, and a
205 amino acid extracellular domain (ECD). The human 4-1BBL ECD shares 32%
and 35%a.a. identity with murine and rat ECD.
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Amino Acid
Sequence
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REGPELSPDD PAGLLDLRQG MFAQLVAQNV
LLIDGPLSWY SDPGLAGVSL TGGLSYKEDT KELVVAKAGV YYVFFQLELR RVVAGEGSGS VSLALHLQPL
RSAAGAAALA LTVDLPPASS EARNSAFGFQ GRLLHLSAGQ RLGVHLHTEA RARHAWQLTQ GATVLGLFRV
TPEIPAGLPS PRSE
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包装清单:
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产品编号
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产品名称
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包装
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XY394-5μg
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Recombinant
Human 4-1BBL/TNFSF9
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5μg
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XY394-20μg
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Recombinant
Human 4-1BBL/TNFSF9
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20μg
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XY394-100μg
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Recombinant
Human 4-1BBL/TNFSF9
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100μg
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XY394-1mg
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Recombinant
Human 4-1BBL/TNFSF9
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1mg
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-
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说明书
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1份
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保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品**于专业人员的科学研究用，不得用于临床诊断或**，不得用于食品或药品，不得存放于普通住宅内。
为了您的**和健康，请穿实验服并戴一次性手套操作。