Recombinant Human TWEAK Receptor/TNFRSF12A
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产品名称: Recombinant Human TWEAK Receptor/TNFRSF12A
产品型号:
产品展商: XYbscience
产品文档: 无相关文档
简单介绍
Recombinant Human TWEAK Receptor/TNFRSF12A由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。Recombinant Human TWEAK Receptor/TNFRSF12A所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
Recombinant Human TWEAK Receptor/TNFRSF12A
的详细介绍
Recombinant Human TWEAK Receptor/TNFRSF12A
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产品编号
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产品名称
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产品包装
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产品价格
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XY385-1mg
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Recombinant
Human TWEAK Receptor/TNFRSF12A
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1mg
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15444.00元
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Species
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Gene ID
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Accession
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Source
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Length
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MW
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Tag
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Human
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51330
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Q9NP84
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E. coli
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53aa
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5.6kDa
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－
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About this
Antibody
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Name
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Recombinant
Human TWEAK Receptor/TNFRSF12A (Recombinant Human TNF-related Weak Inducer of
Apoptosis Receptor; rHuTWEAK Receptor)；重组人肿瘤坏死因子相关的弱受体细胞凋亡的诱导/TNFRSF12A
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Synonyms
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CD266; Fn14;
TNFRSF12; TNFRSF12A; CD266; CD266 antigen; FGF-inducible 14; Fibroblast
growth factor-inducible immediate-early response protein 14; FN14tumor
necrosis factor receptor superfamily member 12A; tumor necrosis factor
receptor superfamily, member 12A; TWEAKR; TweakR; tweak-receptor;
Tweak-receptor; type I transmembrane protein Fn14
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Purity
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>95% by
SDS-PAGE and HPLC analyses.
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Biological
Activity
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Fully
biologically active when compared to standard. The ED50 as determined by
inhibiting TWEAKdependent proliferation of human umbilical vein endothelial
cells (HUVEC) is less than 30ng/ml, corresponding to a specific activity of
>3.3×104IU/mg, in the presence of 15ng/ml of
rHuTWEAK.
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Physical
Appearance
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Sterile
Filtered White lyophilized (freeze-dried) powder.
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Formulation
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Lyophilized
from a 0.2μm filtered concentrated solution in PBS, pH7.4.
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Endotoxin
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Less than 1EU/μg of rHuTWEAK Receptor as determined by LAL method.
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Reconstitution
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We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled water or aqueous buffer
containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions
should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in
appropriate buffered solutions.
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Category
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Cytokine
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Background
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Human
TNF-related weak inducer of apoptosis receptor (TWEAKR) also known as Tumor
necrosis factor receptor superfamily member 12A precursor (gene name
TNFRSF12A) or fibroblast growth factor-inducable 14kDa protein, is distantly
related to the TNFR family, containing one cysteine-rich domain in the
extracellular region and a TNFR-associated factor binding domain but does not
contain a death domain (DD) cytoplasmic region. It is expressed in the
spleen, thymus, peripheral blood lymphocytes, colon, and small intestine.
Signal transduction by TWEAK receptor can be activated by either the membrane
anchored or the soluble TWEAK. In addition, It plays a role in TWEAK-induced
endothelial cell migration, proliferation, and angiogenesis. Human and mouse
TWEAK R share 82%a.a. sequence identity.
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Amino Acid
Sequence
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EQAPGTAPCS RGSSWSADLD KCMDCASCRA
RPHSDFCLGC AAAPPAPFRL LWP
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包装清单:
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产品编号
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产品名称
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包装
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XY385-5μg
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Recombinant
Human TWEAK Receptor/TNFRSF12A
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5μg
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XY385-25μg
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Recombinant
Human TWEAK Receptor/TNFRSF12A
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25μg
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XY385-100μg
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Recombinant
Human TWEAK Receptor/TNFRSF12A
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100μg
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XY385-1mg
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Recombinant
Human TWEAK Receptor/TNFRSF12A
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1mg
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-
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说明书
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1份
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保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品**于专业人员的科学研究用，不得用于临床诊断或**，不得用于食品或药品，不得存放于普通住宅内。
为了您的**和健康，请穿实验服并戴一次性手套操作。