Recombinant Human IL-8, 77a.a/CXCL8
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产品名称: Recombinant Human IL-8, 77a.a/CXCL8
产品型号:
产品展商: XYbscience
产品文档: 无相关文档
简单介绍
Recombinant Human IL-8, 77a.a/CXCL8由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。Recombinant Human IL-8, 77a.a/CXCL8所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
Recombinant Human IL-8, 77a.a/CXCL8
的详细介绍
Recombinant Human IL-8, 77a.a/CXCL8
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产品编号
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产品名称
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产品包装
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产品价格
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XY156-1mg
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Recombinant
Human IL-8, 77a.a/CXCL8
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1mg
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15444.00元
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Species
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Gene ID
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Accession
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Source
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Length
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MW
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Tag
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Human
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3576
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P10145
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E. coli
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77aa
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8.9kDa
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－
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About this
protein
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Name
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Recombinant
Human IL-8, 77a.a/CXCL8 (Recombinant Human Interleukin-8, 77a.a./CXCL8;
rHuIL-8, 77a.a./CXCL8)；重组人白细胞介素8，77a.a./CXCL8
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Synonyms
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GCP-1; GCP1;
IL8; LECT; LUCT; LYNAP; MDNCF; MONAP; NAF; NAP-1; NAP1
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Purity
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>96% by
SDS-PAGE and HPLC analyses.
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Biological
Activity
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Fully
biologically active when compared to standard. The ED50 as determined by a
chemotaxis bioassay using human CXCR2 transfected mouse BaF3 cells is less
than 2ng/ml, corresponding to a specific activity of >5.0×105IU/mg.
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Physical
Appearance
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Sterile
Filtered White lyophilized (freeze-dried) powder.
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Formulation
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Lyophilized
from a 0.2μm filtered concentrated solution in PBS, pH7.4.
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Endotoxin
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Less than 1EU/μg of rHuIL-8, 77a.a./CXCL8 as determined by LAL method.
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Reconstitution
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We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing
0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be
apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in
appropriate buffered solutions.
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Category
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Cytokine
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Background
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Interleukin-8
(IL-8) is encoded by the IL8 gene and produced by macrophages and other cell
types such as epithelial cells. It is also synthesized by endothelial cells,
which store IL-8 in their storage vesicles. There are many receptors capable
to bind IL-8, the most affinity to IL-8 are receptors CXCR1, and CXCR2. As a
member of the CXC chemokine family, function of IL-8 is the induction of
chemotaxis in its target cells, like neutrophil granulocytes, basophils, and
T-cells. IL-8 (72a.a.) has a 5-10 fold higher activity on neutrophil
activation, compared to IL-8 (77a.a.). IL-8 is often associated with
inflammation, it has been cited as a proinflammatory mediator in gingivitis
and psoriasis.
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Amino Acid
Sequence
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AVLPRSAKEL RCQCIKTYSK PFHPKFIKEL
RVIESGPHCA NTEIIVKLSD GRELCLDPKE NWVQRVVEKF LKRAENS
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包装清单:
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产品编号
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产品名称
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包装
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XY156-5μg
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Recombinant
Human IL-8, 77a.a/CXCL8
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5μg
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XY156-25μg
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Recombinant
Human IL-8, 77a.a/CXCL8
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25μg
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XY156-100μg
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Recombinant
Human IL-8, 77a.a/CXCL8
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100μg
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XY156-1mg
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Recombinant
Human IL-8, 77a.a/CXCL8
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1mg
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-
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说明书
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1份
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保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品**于专业人员的科学研究用，不得用于临床诊断或**，不得用于食品或药品，不得存放于普通住宅内。
为了您的**和健康，请穿实验服并戴一次性手套操作。