TBC结构域TBC1蛋白抗体
规格：1mg/1ml
英文名： TBC1D1
别名： KIAA1108; TBC 1; TBC; TBC1 (tre 2/USP6, BUB2, cdc16) domain family, member 1; TBC1; TBC1 domain family member 1; Tbc1d1; TBCD1_HUMAN.
分子量： 133kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TBC1D1
交叉反应：Human, Mouse, Rat, Cow, Guinea Pig,
细胞定位：细胞核
TBC结构域TBC1蛋白抗体产品介绍：background: TBC1D1 is the founding member of a family of proteins sharing a 180- to 200-amino acid TBC domain presumed to have a role in regulating cell growth and differentiation. These proteins share significant homology with TRE2 (USP6; MIM 604334), yeast Bub2, and CDC16 (MIM 603461) (White et al., 2000 [PubMed 10965142]).[supplied by OMIM, Mar 2008] Function: May act as a GTPase-activating protein for Rab family protein(s). May play a role in the cell cycle and differentiation of various tissues. Subcellular Location: Nucleus. Post-translational modifications: Insulin-stimulated phosphorylation by AKT family kinases stimulates SLC2A4/GLUT4 TBC结构域TBC1蛋白抗体translocation. Similarity: Contains 1 PID domain. Contains 1 Rab-GAP TBC domain. Database links: Entrez Gene: 23216 Human Entrez Gene: 57915 Mouse Entrez Gene: 360937 Rat Omim: 609850 Human SwissProt: O97790 Cow SwissProt: Q86TI0 TBC结构域TBC1蛋白抗体Human SwissProt: Q60949 Mouse Unigene: 176503 Human Unigene: 286353 Mouse Unigene: 234365 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
TBC结构域TBC1蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid