AGXT2L2蛋白抗体
规格：1mg/1ml
英文名： AGXT2L2
别名： Alanine glyoxylate aminotransferase 2 like 2; MGC117348; AT2L2_HUMAN.
分子量： 50kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human AGXT2L2
交叉反应：Human, Mouse, Rat, Sheep,
细胞定位：
AGXT2L2蛋白抗体产品介绍：background: Members of the class-III pyridoxal-phosphate-dependent aminotransferase family, such as AGXT2, catalyze the conversion of glyoxylate to glycine using L-alanine as the amino donor. AGXT2 protects from asymmetric dimethylarginine (ADMA)-induced inhibition in nitric oxide (NO) production. Elevated blood concentrations of ADMA, a methyl derivate of the amino acid arginine and an endogenous inhibitor of nitric oxide (NO) synthase, is produced by the physiological degradation of methylated proteins and is found in association with diabetes, hypertension, congestive heart failure and atherosclerosis. AGXT2L2 (alanine-glyoxylate aminotransferase 2-like 2)AGXT2L2蛋白抗体 is a 450 amino acid pyridoxal phosphate that exists as a homotetramer. Belonging to the class-III pyridoxal-phosphate-dependent aminotransferase family, AGXT2L2 localizes to the mitochondria and exists as three alternatively spliced isoforms.AGXT2L2蛋白抗体 Encoded by a gene located on human chromosome 5q35.3, AGXT2L2 may have similar functions as AGXT2. Function: Catalyzes the pyridoxal-phosphate-dependent breakdown of 5-phosphohydroxy-L-lysine, converting it to ammonia, inorganic phosphate and 2-aminoadipate semialdehyde. Subunit: Homotetramer. Subcellular Location: Mitochondrial Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. Database links: UniProtKB/Swiss-Prot: Q8IUZ5.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
AGXT2L2蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 细胞生物 **学 糖尿病
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid