赖氨酰氧化酶样3抗体
规格：1mg/1ml
英文名： LOXL3
别名： LOXL; Loxl3; LOXL3_HUMAN; Lysyl oxidase homolog 3; Lysyl oxidase like 3; Lysyl oxidase-like protein 3.
分子量： 80kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human LOXL3
交叉反应：Human, Mouse, Pig, Cow, Horse, Rabbit,
细胞定位：分泌型蛋白
赖氨酰氧化酶样3抗体产品介绍：background: This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Alternatively spliced transcript variants of this gene have been reported but their full-length nature has not been determined. [provided by 赖氨酰氧化酶样3抗体RefSeq, Jul 2008] Subcellular Location: Secreted > extracellular space. Tissue Specificity: Expressed in many tissues, the highest levels among the tissues studied being seen in the placenta, heart, ovary, testis, small intestine and spleen. Post-translational modifications: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by赖氨酰氧化酶样3抗体 oxidation of tyrosine. Similarity: Belongs to the lysyl oxidase family. Contains 4 SRCR domains. Gene ID: 84695 Database links: Entrez Gene: 84695 Human Omim: 607163 Human SwissProt: P58215 Human Unigene: 727659 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
赖氨酰氧化酶样3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid