组织胺N-甲基转移酶抗体
规格：1mg/1ml
英文名： HNMT
别名： EC 2.1.1.8; Histamine N methyltransferase; Histamine N-methyltransferase; HMT; Hnmt; HNMT S1; HNMT S2; HNMT_HUMAN.
分子量： 33kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human HNMT
交叉反应：Human, Mouse, Rat, Dog, Pig, Horse, Sheep,
细胞定位：细胞浆
组织胺N-甲基转移酶抗体产品介绍：background: In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for组织胺N-甲基转移酶抗体 this gene. [provided by RefSeq, Jul 2008] Function: Inactivates histamine by N-methylation. Plays an组织胺N-甲基转移酶抗体 important role in degrading histamine and in regulating the airway response to histamine. Subcellular Location: Cytoplasm. Similarity: Belongs to the methyltransferase superfamily. HNMT family. Gene ID: 3176 Database links: Entrez Gene: 3176 Human Omim: 605238 Human SwissProt: P50135 Human Unigene: 42151 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
组织胺N-甲基转移酶抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid