组织相容性抗原DQB2抗体
规格：1mg/1ml
英文名： HLA-DQB2
别名： DV19.1 (major histocompatibility complex, class II, DQ beta 2 (HLA-DXB)); DX-beta; HLA class II histocompatibility antigen, DQ beta 2 chain; HLA class II histocompatibility antigen, DX beta chain; HLA
分子量： 27kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human HLA-DQB2
交叉反应：Human,
细胞定位：细胞膜
组织相容性抗原DQB2抗体产品介绍：background: HLA-DQB2 belongs to the family of HLA class II beta chain paralogs. Class II molecules are heterodimers consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. They play a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). Polymorphisms in the alpha and beta chains specify the peptide binding specificity, and typing for these polymorphisms is routinely done for bone marrow transplantation. However this gene, HLA-DQB2, is not routinely typed, as it is not thought to have an effect on transplantation. There is conflicting evidence in the literature and public sequence databases for the protein-coding capacity 组织相容性抗原DQB2抗体of HLA-DQB2. Because there is evidence of transcription and an intact ORF, HLA-DQB2 is represented in Entrez Gene and in RefSeq as a protein-coding locus. [provided by RefSeq, Oct 2010] Function: Belongs to the MHC class II family. Contains one Ig like C1 type 组织相容性抗原DQB2抗体(immunoglobulin like) domain. Subcellular Location: Cell membrane; Single pass type I membrane protein Tissue Specificity: Restricted to skin Langerhans cells (at protein level). Similarity: Belongs to the MHC class II family. Contains 1 Ig-like C1-type (immunoglobulin-like)domain. Gene ID: 3120 Database links: Entrez Gene: 3120 Human Omim: 615161 Human SwissProt: P05538 Human Unigene: 731563 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
组织相容性抗原DQB2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid