CRYM蛋白抗体
规格:1mg/1ml
英文名: mu Crystallin
别名: CRYM; CRYM_HUMAN; Crystallin mu; DFNA 40; DFNA40; Ketimine reductase; Mu crystallin homolog; Mu-crystallin homolog; NADP regulated thyroid hormone binding protein; NADP-regulated thyroid-hormone-bindi
分子量: 34kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human mu Cryst
交叉反应:Human, Mouse, Rat, Pig, Cow, Sheep, Cat,
细胞定位:细胞浆
CRYM蛋白抗体产品介绍:background: Crystallins are separated into two classes: taxon-specific and ubiquitous. The former class is also called phylogenetically-restricted crystallins. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. This gene encodes a taxon-specific crystallin protein that binds NADPH and has sequence similarity to bacterial ornithine cyclodeaminases. The encoded protein does not perform a structural role in lens tissue, and instead it binds thyroid hormone for possible regulatory or developmental roles. Mutations in this gene have been associated with autosomal dominant CRYM蛋白抗体non-syndromic deafness. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2010] Function: Binds thyroid hormone. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors. Subcellular Location: Cytoplasm. Tissue Specificity: Expressed in neural tissue, muscle and kidney. Similarity: Belongs to the ornithine cyclodeaminase family. Gene ID: 1428 Database links: Entrez Gene: 1428 Human Entrez Gene: 505167 Cow Entrez Gene: 12971 Mouse Entrez Gene: 117024 RCRYM蛋白抗体at Omim: 123740 Human SwissProt: Q14894 Human SwissProt: O54983 Mouse SwissProt: Q9QYU4 Rat Unigene: 924 Human Unigene: 9114 Mouse Unigene: 24561 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
CRYM蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 发育生物学 生长因子和** 结合蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid