GTP结合蛋白7抗体
规格：1mg/1ml
英文名： MTG1/GTPBP7
别名： GTP; GTP binding protein; GTP binding protein 7 (putative); GTP binding protein 7; GTP-binding protein 7 (putative); GTP-binding protein 7; GTPBP7; Mitochondrial GTPase 1; mitochondrial GTPase 1 homol
分子量： 37kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MTG1/GTP
交叉反应：Human, Mouse, Rat, Cow,
细胞定位：
GTP结合蛋白7抗体产品介绍：background: MTH1 is a 179 amino acid cytoplasmic protein that is a member of the nudix hydrolase family. Highly expressed in testis, thymus and proliferating blood lymphocytes, MTH1 functions as an antimutagenic that hydrolyzes oxidized purine nucleoside triphosphates to their corresponding monophosphates. Through its ability to enzymatically hydrolyze ATP and GTP to AMP and GMP, respectively, MTH1 prevents misincorporation of GTP into DNA, thus preventing A:T to C:G transversions. The cytoplasmic location of MTH1, along with its antimutagenic capabilities, suggests that it may also be involved in the sanitization of nucleotide pools for both mitochondrial and nuclear genomes. Four isoforms of MTH1 exist—three of which are formed due to alternative splicing events and one of which isGTP结合蛋白7抗体 formed via a single-nucleotide polymorphism. Overexpression of MTH1 is implicated in prostate and cell lung carcinomas Function: Mitochondrial GTPase. May be involved in assembly of the large ribosomal subunit. Subcellular Location: Mitochondrion. Similarity: Belongs to the MMR1/HSR1 GTP-binding protein family. MTG1 subfamily. Contains 1 G (guanine nucleotide-binding) domain. Gene ID: 92170 Database links: Entrez GTP结合蛋白7抗体Gene: 92170 Human Entrez Gene: 509768 Cow Entrez Gene: 212508 Mouse SwissProt: Q4PS77 Cow SwissProt: Q9BT17 Human SwissProt: Q8R2R6 Mouse Unigene: 501578 Human Unigene: 296088 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
GTP结合蛋白7抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 转录调节因子 转运蛋白 线粒体 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid