死亡因子4样蛋白2抗体
规格：1mg/1ml
英文名： Mortality Factor 4 like 2
别名： KIAA0026; MO4L2_HUMAN; MORF related gene X protein; MORF-related gene X protein; Morf4l2; MORFL2; Mortality factor 4 like protein 2; Mortality factor 4-like protein 2; MRGX; MSL3 2 protein; Protein MS
分子量： 35kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Mortalit
交叉反应：Human, Mouse, Rat, Pig, Horse, Saccharomyces cerevisiae
细胞定位：细胞核
死亡因子4样蛋白2抗体产品介绍：background: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones. Function: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally死亡因子4样蛋白2抗体 by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component 死亡因子4样蛋白2抗体of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones. Subcellular Location: Nucleus. Similarity: Belongs to the MRG family. Gene ID: 9643 Database links: Entrez Gene: 9643 Human Entrez Gene: 56397 Mouse Entrez Gene: 317413 Rat Omim: 300409 Human SwissProt: Q15014 Human SwissProt: Q9R0Q4 Mouse SwissProt: Q6QI89 Rat Unigene: 326387 Human Unigene: 27218 Mouse Unigene: 6961 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
死亡因子4样蛋白2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导 细胞凋亡 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid