酮戊二酸脱氢酶OGDH抗体
规格：1mg/1ml
英文名： OGDH
别名： 2 oxoglutarate dehydrogenase; 2 oxoglutarate dehydrogenase complex component E1; 2 oxoglutarate dehydrogenase mitochondrial; 2-oxoglutarate dehydrogenase; 2-oxoglutarate dehydrogenase complex componen
分子量： 111kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
酮戊二酸脱氢酶OGDH抗体**原：KLH conjugated synthetic peptide derived from human OGDH
交叉反应：Human, Pig, Cow, Horse, Sheep,
细胞定位：细胞浆
产品介绍：background: This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct酮戊二酸脱氢酶OGDH抗体 isoforms.[provided by RefSeq, Sep 2009] Function: The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3). Subcellular Location: Mitochondrion matrix. Similarity: Belongs to the 酮戊二酸脱氢酶OGDH抗体alpha-ketoglutarate dehydrogenase family. Gene ID: 4967 Database links: Entrez Gene: 4967 Human Entrez Gene: 18293 Mouse Entrez Gene: 534599 Cow Entrez Gene: 360975 Rat Omim: 613022 Human SwissProt: Q148N0 Cow SwissProt: Q02218 Human SwissProt: Q60597 Mouse SwissProt: Q5XI78 Rat Unigene: 488181 Human Unigene: 276348 Mouse Unigene: 472458 Mouse Unigene: 45991 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
酮戊二酸脱氢酶OGDH抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 信号转导 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid