转录因子Sp2抗体
规格:1mg/1ml
英文名: SP2 transcription factor
别名: Kiaa0048; OTTHUMP00000196580; SP2; SP2_HUMAN; SPECIFICITY PROTEIN 2; Transcription factor Sp2.
分子量: 65kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human SP2 tran
交叉反应:Human, Mouse,
细胞定位:细胞核
转录因子Sp2抗体产品介绍:background: This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein contains the least conserved DNA-binding domain within the Sp subfamily of proteins, and its DNA sequence specificity differs from the other Sp proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can 转录因子Sp2抗体activate or in some cases repress expression from different promoters. [provided by RefSeq, Jul 2008] Function: Binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites. Subcellular Location转录因子Sp2抗体: Nucleus. Similarity: Belongs to the Sp1 C2H2-type zinc-finger protein family. Contains 3 C2H2-type zinc fingers. Gene ID: 6668 Database links: Entrez Gene: 6668 Human Entrez Gene: 78912 Mouse Omim: 601801 Human SwissProt: Q02086 Human SwissProt: Q9D2H6 Mouse Unigene: 514276 Human Unigene: 482333 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
转录因子Sp2抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:转录调节因子 结合蛋白 锌指蛋白 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid