抗氧化蛋白1抗体
规格：1mg/1ml
英文名： OXR1
别名： C7; C7B; Gm1238; Nbla00307; Nucleolar protein C7; Oxidation resistance 1; Oxidation resistance protein 1; Oxr1; OXR1_HUMAN; Putative protein product of Nbla00307; rCG_59825.
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human OXR1
交叉反应：Human, Mouse, Rat,
细胞定位：
抗氧化蛋白1抗体产品介绍：background: Reactive oxygen species (ROS) are highly reactive molecules that are a normal consequence of aerobic metabolism. Cellular ROS damage can induce apoptosis and spontaneous mutagenesis. Oxr1 (Oxidation resistance protein 1) is a 758 amino acid mitochondrial protein that is most likely involved in protection from oxidative damage. Oxr1 is highly conserved from yeast to humans and is specific to eukaryotes.Induced by heat and oxidative stress, the carboxyl-terminal half of Oxr1 is required for its function. Upregulation of superoxide dismutase and catalase was observed in developing drosophila mutants that lacked the gene encoding Oxr1,抗氧化蛋白1抗体 suggesting that oxidative stress may trigger compensatory protein expression. There are four isoforms of Oxr1 that are produced as a result of alternative splicing events. Function: May be involved in protection from oxidative damage. Subcellular Location: Mitochondrion. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Belongs to the OXR1 family. Contains 1 GRAM domain.抗氧化蛋白1抗体 Contains 1 LysM repeat. Contains 1 TLD domain. Database links: Entrez Gene: 55074 Human Entrez Gene: 170719 Mouse Entrez Gene: 117520 Rat Omim: 605609 Human SwissProt: Q8N573 Human SwissProt: Q4KMM3 Mouse SwissProt: Q4V8B0 Rat Unigene: 127286 Human Unigene: 740427 Human Unigene: 254267 Mouse Unigene: 4252 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
抗氧化蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid