信号诱导增殖相关蛋白1样蛋白1抗体
规格：1mg/1ml
英文名： SIPA1L1
别名： DKFZp686G1344; E6 targeted protein 1; E6TP1; H_DJ1140G11.1; High risk human papilloma viruses E6 oncoproteins targeted protein 1; KIAA0440; Signal induced proliferation associated 1 like 1; Signal ind
分子量： 200kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SIPA1L1
交叉反应：Human, Mouse, Rat,
细胞定位：
信号诱导增殖相关蛋白1样蛋白1抗体产品介绍：background: SIPA1L1 (Signal-induced proliferation associated-like protein 1) is a member of the SIPA1 family of RapGAPs. SIPA1L1 was initially identified as a binding partner and degradation target of the E6 oncoprotein of high-risk papillomaviruses. Recently, it was discovered that Casein kinase I epsilon (CKIe), a Wnt-regulated kinase that regulates Wnt/b-catenin signaling, also can bind to the carboxy-terminus of SIPA1L1. CKIe phosphorylates SIPA1L1, thereby reducing its stability and alleviating its inhibition of Rap1, a protein required for Wnt8/CKIe-mediated gastrulation during embryogenesis, suggesting SIPA1L1 plays important roles in embryo信号诱导增殖相关蛋白1样蛋白1抗体 development as well as control of cell proliferation. Subcellular Location: Intracellular Database links: Entrez Gene: 26037 Human Entrez Gene: 217692 Mouse Entrez Gene: 246212 Rat SwissProt: O43166 Human SwissProt: Q8C0T5 Mouse SwissProt:信号诱导增殖相关蛋白1样蛋白1抗体 O35412 Rat Unigene: 654657 Human Unigene: 261333 Mouse Unigene: 10835 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
信号诱导增殖相关蛋白1样蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 发育生物学 信号转导 干细胞 **及病毒 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid