SHQ1蛋白抗体
规格:1mg/1ml
英文名: SHQ1
别名: FLJ10539; Protein SHQ1 homolog; shq1; SHQ1 homolog (S. cerevisiae); SHQ1 homolog; SHQ1, H/ACA ribonucleoprotein assembly factor; SHQ1_HUMAN; Shq1p.
分子量: 65kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human SHQ1
交叉反应:Human, Mouse, Rat,
细胞定位:细胞浆
SHQ1蛋白抗体产品介绍:background: SHQ1 assists in the assembly of H/ACA-box ribonucleoproteins that function in the processing of ribosomal RNAs, modification of spliceosomal small nuclear RNAs, and stabilization of telomerase (see MIM 602322) (Grozdanov et al., 2009 [PubMed 19383767]).[supplied by OMIM, Dec 2010] Function: Required for the quantitative accumulation of H/ACA ribonucleoproteins (RNPs), including telomerase, probably through the stabilization of DKC1, from the time of its synthesis until its association with NOP10,SHQ1蛋白抗体 NHP2, and NAF1 at the nascent H/ACA RNA. Subcellular Location: Cytoplasm > cytosol. Nucleus > nucleoplasm. May at least partially shuttle between cytosol and nucleoplasm. In the nucleoplasm, exhibits a granular pattern, but is excluded from nucleoli and Cajal bodies.SHQ1蛋白抗体 Absent from most H/ACA-box RNA transcription sites. Similarity: Belongs to the SHQ1 family. Contains 1 CS domain. Database links: Entrez Gene: 55164 Human Entrez Gene: 72171 Mouse Omim: 613663 Human SwissProt: Q6PI26 Human SwissProt: Q7TMX5 Mouse Unigene: 606584 Human Unigene: 256022 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
SHQ1蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:转录调节因子 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid