艾滋病病毒EP1抗体
规格:1mg/1ml
英文名: HIVEP1
别名: Cirhin interaction protein; CIRIP; CRYBP1; GAAP; Gate keeper of apoptosis-activating protein; HIV EP1; HIV-EP1; HIVEP 1; Hivep1; Human immunodeficiency virus type I enhancer binding protein 1; Human i
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human HIVEP1
交叉反应:Human, Mouse, Rat,
细胞定位:细胞核 细胞浆
艾滋病病毒EP1抗体产品介绍:background: This protein specifically binds to the DNA sequence 5'-GGGACTTTCC-3' which is found in the enhancer elements of numerous viral promoters such as those of SV40, CMV, or HIV-1. In addition, related sequences are found in the enhancer elements of a number of cellular promoters, including those of the class I MHC, interleukin-2 receptor, and interferon-beta genes. It may act in T-cell activation. Involved in activating HIV-1 gene expression. Isoform 2 and isoform 3 also bind to the 艾滋病病毒EP1抗体IPCS (IRF1 and p53 common sequence) DNA sequence in the promoter region of interferon regulatory factor 1 and p53 genes and are involved in transcription regulation of these genes. Isoform 2 does not activate HIV-1 gene expression. Isoform 2 and isoform 3 may be involved in 艾滋病病毒EP1抗体apoptosis. Subcellular Location: Cytoplasm. Nucleus and Nucleus. Similarity: Contains 5 C2H2-type zinc fingers. Gene ID: 3096 Database links: Entrez Gene: 3096 Human Omim: 194540 Human SwissProt: P15822 Human Unigene: 567284 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
艾滋病病毒EP1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 转录调节因子 结合蛋白 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid