核小体相关激酶HIPK1抗体
规格：1mg/1ml
英文名： HIPK1
别名： Hipk 1; Hipk1; HIPK1_HUMAN; Homeodomain interacting protein kinase 1; Homeodomain interacting protein kinase 1 like protein; Homeodomain-interacting protein kinase 1; Myak; Nbak 2; Nbak2; Nuclear body
分子量： 38kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human HIPK1
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse, Macaque Monkey
细胞定位：细胞核 细胞浆
核小体相关激酶HIPK1抗体产品介绍：background: The protein encoded by this gene belongs to the Ser/Thr family of protein kinases and HIPK subfamily. It phosphorylates homeodomain transcription factors and may also function as a co-repressor for homeodomain transcription factors. Alternative splicing results in four transcript variants encoding four distinct isoforms. [provided by RefSeq, Jul 2008] Function: May play a role as a corepressor for homeodomain transcription factors. Phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm. May be involved in malignant squamous cell tumor formation. Subcellular Location: Nucleus.核小体相关激酶HIPK1抗体 Cytoplasm. Predominantly nuclear. Tissue Specificity: Ubiquitously expressed with highest levels in skeletal muscle and heart. Overexpressed in breast cancer cell lines. Post-translational modifications: Autophosphorylated. Phosphorylated and activated by JNK1. Similarity: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. HIPK subfamily. Contains 1 protein kinase domain. Database links:核小体相关激酶HIPK1抗体 Entrez Gene: 512233 Cow Entrez Gene: 475803 Dog Entrez Gene: 204851 Human Entrez Gene: 15257 Mouse Entrez Gene: 365895 Rat Omim: 608003 Human SwissProt: Q86Z02 Human SwissProt: O88904 Mouse SwissProt: A4L9P5 Rat Unigene: 532363 Human Unigene: 20827 Mouse Unigene: 4151 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产核小体相关激酶HIPK1抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 激酶和磷酸酶 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid