神经细胞早期基因抗体
规格:1mg/1ml
英文名: Homer (1b+1c)
别名: Homer 1; HOMER; Homer homolog 1; Homer protein homolog 1; Homer1; HOMER1B; HOMER1C; Neuronal immediate early gene; SYN47; Ves 1. HOME1_HUMAN
分子量: 45kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Homer (1
交叉反应:Human, Mouse, Rat, Cow, Horse, Sheep,
细胞定位:细胞浆
神经细胞早期基因抗体产品介绍:background: This gene encodes a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function. [provided by RefSeq, Jul 2008] Function: Homer is a neuronal immediate early gene that is enriched at excitatory synapses and selectively binds metabotropic glutamate receptors. Subunit: Interacts with GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2,SHANK1 and SHANK3. Interacts with IFT57 and OPHN1. Isoform 1 encodes a coiled-coil 神经细胞早期基因抗体structure that mediates homo- and heteromultimerization. Subcellular Location: Cytoplasmic; Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Note=Postsynaptic density of neuronal cells. Isoform 1 inhibits surface expression of GRM5 causing it to be retained in the endoplasmic reticulum. Similarity: Belongs to the Homer family. Contains 1 WH1 domain. Gene ID: 9456 Database links: 神经细胞早期基因抗体Entrez Gene: 9456 Human Entrez Gene: 26556 Mouse Entrez Gene: 29546 Rat Omim: 604798 Human SwissProt: Q86YM7 Human SwissProt: Q9Z2Y3 Mouse SwissProt: Q9Z214 Rat Unigene: 591761 Human Unigene: 37500 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
神经细胞早期基因抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 神经生物学 细胞类型标志物
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid