异质核核糖核蛋白U样蛋白1抗体
规格：1mg/1ml
英文名： HNRPUL1
别名： Adenovirus early region 1B associated protein 5; Adenovirus early region 1B-associated protein 5; E130317O14Rik; E1B 55 kDa associated protein 5; E1B AP5; E1B-55 kDa-associated protein 5; E1B-AP5; E1B
分子量： 96kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human HNRPUL1
交叉反应：Human, Mouse, Rat, Cow, Horse, Cat,
细胞定位：细胞核
异质核核糖核蛋白U样蛋白1抗体产品介绍：background: This gene encodes a nuclear RNA-binding protein of the heterogeneous nuclear ribonucleoprotein (hnRNP) family. This protein binds specifically to adenovirus E1B-55kDa oncoprotein. It may play an important role in nucleocytoplasmic RNA transport, and its function is modulated by E1B-55kDa in adenovirus-infected cells. Two transcript variants encoding different isoforms have been found for this gene. Additional variants have also been found, but their full-length natures have not been determined. [provided by RefSeq, Jul 2008] Function: Acts as a basic transcriptional regulator. Represses basic transcription driven by several 异质核核糖核蛋白U样蛋白1抗体virus and cellular promoters. When associated with BRD7, activates transcription of glucocorticoid-responsive promoter in the absence of ligand-stimulation. Plays also a role in mRNA processing and transport. Binds avidly to poly(G) and poly(C) RNA homopolymers in vitro. Subcellular Location: Nucleus. Post-translational modifications: Methylated. Similarity: Contains 1 B30.2/SPRY domain. Contains 1异质核核糖核蛋白U样蛋白1抗体 SAP domain. Gene ID: 11100 Database links: Entrez Gene: 11100 Human Entrez Gene: 232989 Mouse Entrez Gene: 361522 Rat Omim: 605800 Human SwissProt: Q9BUJ2 Human SwissProt: Q8VDM6 Mouse Unigene: 155218 Human Unigene: 718642 Human Unigene: 254223 Mouse Unigene: 95170 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
异质核核糖核蛋白U样蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 转录调节因子 结合蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid