异质核糖核蛋白A3抗体
规格：1mg/1ml
英文名： hnRNP A3
别名： FBRNP; HNRPA3; ROA3_HUMAN; Heterogeneous nuclear ribonucleoprotein A3; HNRPA3.
分子量： 40kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human hnRNP A3
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse, Rabbit,
细胞定位：细胞核
产异质核糖核蛋白A3抗体品介绍：background: Heterogeneous nuclear ribonucleoproteins (hnRNPs) constitute a set of poly-peptides that contribute to mRNA transcription and pre-mRNA processing as well as mature mRNA transport to the cytoplasm and translation. They also bind heterogeneous nuclear RNA (hnRNA), which are the transcripts produced by RNA polymerase II. There are approximately 20 known hnRNP proteins, and their complexes are the major constituents of the spliceosome. The majority of hnRNP protein components are localized to the nucleus; however some shuttle between the nucleus and the cytoplasm. The A/B subfamily of hnRNPs include A1, A2/B1, A3 and A0, and in Xenopus, hnRNP A1, A2 and A3 are ubiquitously expressed throughout development as well as in ***** tissues. hnRNP A1 and A2/B1 regulate the processing 异质核糖核蛋白A3抗体of pre-mRNA by directly antagonizing the association of various splicing factors and by influencing the splice site selection on pre-mRNA. The hnRNP A0 gene is distinct from the other A/B family members, and it encodes a low-abundance protein, which is implicated in mRNA stability. Function: HNRPA3 plays a role in cytoplasmic trafficking of RNA. It binds to the cis-acting response element(A2RE) and may be异质核糖核蛋白A3抗体 involved in pre-mRNA splicing. Subunit: Identified in the spliceosome C complex. Subcellular Location: Nuclear Similarity: Contains 2 RRM (RNA recognition motif) domains. Gene ID: 220988 Database links: Entrez Gene: 220988 Human Entrez Gene: 229279 Mouse Entrez Gene: 362152 Rat Omim: 605372 Human SwissProt: P51991 Human SwissProt: Q8BG05 Mouse SwissProt: Q6URK4 Rat Unigene: 516539 Human Unigene: 107690 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
异质核糖核蛋白A3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 结合蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid