磷酸化异质核糖核蛋白K抗体
规格：1mg/1ml
英文名： phospho-hnRNP K (Ser284)
别名： hnRNP K (phospho S284); p-hnRNP K (phospho S284); CSBP; dC stretch binding protein; FLJ41122; Heterogeneous nuclear ribonucleoprotein K; hnRNP K; HNRNPK; HNRPK; HNRPK_HUMAN; Transformation up regulate
分子量： 51kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human phospho-
交叉反应：Human, Mouse, Rat, Chicken, Cow, Horse, Sheep,
细胞定位：细胞核 细胞浆
磷酸化异质核糖核蛋白K抗体产品介绍：background: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference; it binds tenaciously to poly(C). This protein is磷酸化异质核糖核蛋白K抗体 also thought to have a role during cell cycle progession. Several alternatively spliced transcript variants have been described for this gene, however, not all of them are fully characterized. [provided by RefSeq, Jul 2008] Function: One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain 磷酸化异质核糖核蛋白K抗体cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Subcellular Location: Cytoplasm. Nucleus > nucleoplasm. In case of ASFV infection, there is a shift in the localization which becomes predominantly nuclear. Post-translational modifications: Arg-296 and Arg-299 are dimethylated, probably to asymmetric dimethylarginine. Similarity: Contains 3 KH domains. Gene ID: 3190 Database links: Entrez Gene: 3190 Human Entrez Gene: 15387 Mouse Omim: 600712 Human SwissProt: P61978 Human SwissProt: P61979 Mouse Unigene: 522257 Human Unigene: 142872 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
磷酸化异质核糖核蛋白K抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid